http://www.cnr.it/ontology/cnr/individuo/prodotto/ID282230

Multiparametric evaluation of the acoustic behavior of halloysite nanotubes for medical echographic image enhancement (Articolo in rivista)

Type

Articolo in rivista (Classe)
Prodotto della ricerca (Classe)

Label

Multiparametric evaluation of the acoustic behavior of halloysite nanotubes for medical echographic image enhancement (Articolo in rivista) (literal)

Anno

2014-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

10.1109/TIM.2013.2287797 (literal)

Alternative label

Soloperto G.[ 1,2 ]; Conversano F.[ 1,2 ]; Greco A.[ 1,2 ]; Casciaro E.[ 1,2 ]; Ragusa A.[ 3 ]; Leporatti S.[ 3 ] ; Lay-Ekuakille A.[ 4 ]; Casciaro S.[ 1,2 ] (2014)
Multiparametric evaluation of the acoustic behavior of halloysite nanotubes for medical echographic image enhancement
in IEEE transactions on instrumentation and measurement
(literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

Soloperto G.[ 1,2 ]; Conversano F.[ 1,2 ]; Greco A.[ 1,2 ]; Casciaro E.[ 1,2 ]; Ragusa A.[ 3 ]; Leporatti S.[ 3 ] ; Lay-Ekuakille A.[ 4 ]; Casciaro S.[ 1,2 ] (literal)

Pagina inizio

1423 (literal)

Pagina fine

1430 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url

http://www.scopus.com/inward/record.url?eid=2-s2.0-84903558423&partnerID=q2rCbXpz (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

63 (literal)

Rivista

IEEE transactions on instrumentation and measurement (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

6 (literal)

Note

Scopu (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

[ 1 ] CNR, Inst Clin Physiol, Bioengn Div, I-73100 Lecce, Italy [ 2 ] CNR, Inst Clin Physiol, Nanoimaging Ultrasound LAB, I-73100 Lecce, Italy [ 3 ] CNR, Inst Nanosci, Natl Nanotechnol Lab CNR NANO, I-73010 Lecce, Italy [ 4 ] Univ Salento, Dept Innovat Engn, I-73100 Lecce, Italy (literal)

Titolo

Multiparametric evaluation of the acoustic behavior of halloysite nanotubes for medical echographic image enhancement (literal)

Abstract

Halloysite nanotubes (HNTs) are nanomaterials composed of double layered aluminosilicate minerals characterized by a wide range of medical applications. Nonetheless, systematic investigations of their imaging potential are still poorly documented. This paper shows a parametric assessment of the effectiveness of HNTs as scatterers for safe ultrasound (US)-based molecular imaging. Quantitative evaluation of average signal enhancement produced by HNTs with varying set up configuration was performed. The influence of different levels of power (20%, 50%, and 80%) of the signal emitted by clinical equipment was determined, to assess the efficacy of different HNT concentrations (1.5, 3, and 5 mg/mL) at conventional ultrasonic frequencies (5.7-7 MHz), even in case of specific limitation regarding US mechanical interaction with target tissues. Different samples of HNT containing agarose gel were imaged through a commercially available echographic system and acquired data were processed through a dedicated prototypal platform to extract the average ultrasonic signal amplitude. The rate of signal enhancement achieved by different concentration values was quantified and the contribution of frequency increment was separately evaluated. Despite influencing the level of mechanical excitation on HNTs and tissues, our results demonstrated how increasing the power of the emitted signal negatively affected the measured backscatter. Conversely, noticeable improvements in signal backscatter could be achieved incrementing HNT concentration and the echographic frequency employed; specifically the signal enhancement over the used concentration range could be improved by averagely 20%, corresponding to 4.86 ± 0.80 (a.u.), when employing the higher value of echographic frequency. © 2013 IEEE. (literal)

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