http://www.cnr.it/ontology/cnr/individuo/prodotto/ID277571

Probiotics for the treatment of Helicobacter pylori infection in children (Articolo in rivista)

Type

Label

Probiotics for the treatment of Helicobacter pylori infection in children (Articolo in rivista) (literal)

Anno

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Alternative label

1)Lucia Pacifico,2) John Frederick Osborn,3) Enea Bonci, 1)Sara Romaggioli, 4)Rossella Baldini, 5)Claudio Chiesa (2014)
Probiotics for the treatment of Helicobacter pylori infection in children
in World journal of gastroenterology (Online); Baishideng publishing, Hong Kong (Cina)
(literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

1)Lucia Pacifico,2) John Frederick Osborn,3) Enea Bonci, 1)Sara Romaggioli, 4)Rossella Baldini, 5)Claudio Chiesa (literal)

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Note

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1)Department of Pediatrics and Child Neuropsychiatry, Sapienza University of Rome; 2) Department of Health Sciences and Infectious Diseases, Sapienza University of Rome; 3)Department of Experimental Medicine, Sapienza University of Rome;4)Department of Human Anatomy, Sapienza University of Rome;5) Institute of Translational Pharmacology, National Research Council, 100 00133 Rome, Italy (literal)

Titolo

Probiotics for the treatment of Helicobacter pylori infection in children (literal)

Abstract

The combination of a proton pump inhibitor and two antibiotics (clarithromycin plus amoxicillin or metronidazole) has been the recommended first-line therapy since the first guidelines for Helicobacter pylori (H.pylori ) infection in children were published. In recent years, the success of eradication therapies has declined, in part due to the development of H. pylori resistant strains. Alternative anti-H. pylori treatments are currently becoming more popular than the traditional eradication methods. Components that may be used either as a monotherapy or, in combination with anti-microbials, resulting in a more effective anti-H. pylori therapy have been investigated in depth by several researchers. One of the potential therapies is probiotic cultures; promising results have been observed in initial studies with numerous probiotic strains. Nevertheless, many questions remain unanswered. In this article, we comprehensively review the possible mechanisms of action of probiotics on H. pylori infection, and present the results of published studies using probiotics as possible agents to control H. pylori infection in children. The effect of the addition of probiotics to the standard H. pylori eradication therapy for the prevention of antibiotic associated side-effects is also discussed. (literal)

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