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Characterization and evaluation of silver release from four different dressings used in burns care (Articolo in rivista)
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- Characterization and evaluation of silver release from four different dressings used in burns care (Articolo in rivista) (literal)
- Anno
- 2012-01-01T00:00:00+01:00 (literal)
- Alternative label
Rigo, C. and Roman, M. and Munivrana, I. and Vindigni, V. and Azzena, B. and Barbante, C. and Cairns, W.R.L. (2012)
Characterization and evaluation of silver release from four different dressings used in burns care
in Burns
(literal)
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- Rigo, C. and Roman, M. and Munivrana, I. and Vindigni, V. and Azzena, B. and Barbante, C. and Cairns, W.R.L. (literal)
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- cited By (since 1996)4 (literal)
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- University Ca' Foscari of Venice, Department of Environmental Sciences, Statistics and Informatics, Dorsoduro 2137, 30123 Venice, Italy; Dept. of Neurosci., Neurological, Psychiatric, Sensorial, Reconstructive and Rehabilitative Sciences, via Giustiniani 5, 35128 Padova, Italy; Institute for the Dynamics of Environmental Processes (IDPA-CNR), Dorsoduro 2137, 30123 Venice, Italy; Burns Centre, Division of Plastic Surgery, Hospital of Padova, via Giustiniani 2, 35128 Padova, Italy (literal)
- Titolo
- Characterization and evaluation of silver release from four different dressings used in burns care (literal)
- Abstract
- For centuries silver and silver compounds have been in use to control infection and avoid septicaemia in the care of burns and chronic wounds. Renewed interest has resulted in a number of Ag based dressings that are now widely used in burns centres. Despite extensive use, a systematic study of the chemical composition, release kinetics and biochemical action of these products has yet to be published. In this work we have characterized the morphology of four commercial Ag dressings by scanning electron microscopy and the silver content was determined to range between 1.39 mg/cm2 and 0.03 mg/cm 2. Release kinetics in three different matrices (ultra pure water, normal saline solution and a human serum substitute) were determined. The highest rates were found in serum substitute, with a maximum of 4099 ?g/(h cm2) to a minimum of 0.0001 ?g/(h cm2). Our results show that the mean inhibitory concentrations are exceeded for most common pathogens in serum substitute and sterile water, but the presence of high Cl- concentrations tend to inactivate the dressings. (literal)
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