The poly(ADP-ribosylation) story: A long route from Cinderella to Princess. (Articolo in rivista)

Type
Label
  • The poly(ADP-ribosylation) story: A long route from Cinderella to Princess. (Articolo in rivista) (literal)
Anno
  • 2007-01-01T00:00:00+01:00 (literal)
Alternative label
  • Scovassi AI (2007)
    The poly(ADP-ribosylation) story: A long route from Cinderella to Princess.
    in Rivista di biologia (testo stamp.)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Scovassi AI (literal)
Pagina inizio
  • 351 (literal)
Pagina fine
  • 360 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 100 (literal)
Rivista
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • IGM-CNR (literal)
Titolo
  • The poly(ADP-ribosylation) story: A long route from Cinderella to Princess. (literal)
Abstract
  • Poly(ADP-ribosylation) is a post-translational modification of proteins with a multifunctional role in basic processes, such as DNA repair, transcription, cell proliferation and death. For decades, this reaction was studied by a small community of researchers, devoted to the identification of signals promoting the conversion of the coenzyme NAD into poly(ADP-ribose) and the further degradation of the polymers. The development of specific inhibitors and the discovery of a superfamily of poly(ADP-ribosylating) enzymes have recently conferred a higher importance to this process. The main features of poly(ADP-ribosylation) together with new research perspectives will be discussed. (literal)
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