Chromosome positioning is largely unaffected in lymphoblastoid cell lines containing emerin or A-type lamin mutations. (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Chromosome positioning is largely unaffected in lymphoblastoid cell lines containing emerin or A-type lamin mutations. (Articolo in rivista) (literal)

Anno

• 2005-01-01T00:00:00+01:00 (literal)

Alternative label

• Meaburn KJ, Levy N, Toniolo D, Bridger JM. (2005)
  Chromosome positioning is largely unaffected in lymphoblastoid cell lines containing emerin or A-type lamin mutations.
  in Biochemical Society transactions
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Meaburn KJ, Levy N, Toniolo D, Bridger JM. (literal)

Pagina inizio

• 1438 (literal)

Pagina fine

• 1440 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 33 (literal)

Rivista

• Biochemical Society transactions (Rivista)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Lab. Nuclear and Genomic Health, Cell and Chromosome Biology Group, Division of Biosciences, Brunel University, Uxbridge,U.K.; Inserm U491, Genetique Medicale et Developpement, Faculte de Medecine de la Marseille, Marseille, France; IGM-CNR, (literal)

Titolo

• Chromosome positioning is largely unaffected in lymphoblastoid cell lines containing emerin or A-type lamin mutations. (literal)

Abstract

• Gene-poor human chromosomes are reproducibly found at the nuclear periphery in proliferating cells. There are a number of inner nuclear envelope proteins that may have roles in chromosome location and anchorage, e.g. emerin and A-type lamins. In the last decade, a number of diseases associated with tissue degeneration and premature aging have been linked with mutations in lamin A or emerin. These are termed laminopathies, with mutations in emerin causing Emery-Dreifuss muscular dystrophy. Despite highly aberrant nuclear distributions of A-type lamins and emerin in lymphoblastoid cell lines derived from patients with emerin or lamin A mutations, little or no change in chromosome location was detected. (literal)

Prodotto di

• Malattie genetiche dovute a difetti nella riparazione del DNA che predispongono ai tumori. Analisi genetica funzionale dei fattori importanti per l'integrità del genoma. (ME.P05.005.001) (Modulo)
• Institute of molecular genetics (IGM) (Istituto)

Autore CNR

• DANIELA TONIOLO (Unità di personale interno)

Insieme di parole chiave

• Keywords of "Chromosome positioning is largely unaffected in lymphoblastoid cell lines containing emerin or A-type lamin mutations." (Insieme di parole chiave)

Incoming links:

Prodotto

• Institute of molecular genetics (IGM) (Istituto)
• Malattie genetiche dovute a difetti nella riparazione del DNA che predispongono ai tumori. Analisi genetica funzionale dei fattori importanti per l'integrità del genoma. (ME.P05.005.001) (Modulo)

Autore CNR di

• DANIELA TONIOLO (Unità di personale interno)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Biochemical Society transactions (Rivista)

Insieme di parole chiave di

• Keywords of "Chromosome positioning is largely unaffected in lymphoblastoid cell lines containing emerin or A-type lamin mutations." (Insieme di parole chiave)