Localization of proteins bound to a replication origin of human DNA along the cell cycle (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Localization of proteins bound to a replication origin of human DNA along the cell cycle (Articolo in rivista) (literal)

Anno

• 2003-01-01T00:00:00+01:00 (literal)

Alternative label

• Abdurashidova G, Danilov MB, Ochem A, Triolo G, Radulescu S, Vindigni A, Riva S, Falaschi A (2003)
  Localization of proteins bound to a replication origin of human DNA along the cell cycle
  in EMBO journal (Print)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Abdurashidova G, Danilov MB, Ochem A, Triolo G, Radulescu S, Vindigni A, Riva S, Falaschi A (literal)

Pagina inizio

• 4294 (literal)

Pagina fine

• 4303 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 22 (literal)

Rivista

• EMBO journal (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note

• Impact Factor: 10.456 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• International Centre for Genetic Engineering and Biotechnology, Trieste; Laser Laboratory, Sincrotrone Trieste; Istituto di Genetica Molecolare, Consiglio Nazionale delle Ricerche, Pavia, Italy (literal)

Titolo

• Localization of proteins bound to a replication origin of human DNA along the cell cycle (literal)

Abstract

• The proteins bound in vivo at the human lamin B2 DNA replication origin and their precise sites of binding were investigated along the cell cycle utilizing two novel procedures based on immunoprecipitation following UV irradiation with a pulsed laser light source. In G(1), the pre-replicative complex contains CDC6, MCM3, ORC1 and ORC2 proteins; of these, the post-replicative complex in S phase contains only ORC2; in M phase none of them are bound. The precise nucleotide of binding was identified for the two ORC and the CDC6 proteins near the start sites for leading-strand synthesis; the transition from the pre- to the post-replicative complex is accompanied by a 17 bp displacement of the ORC2 protein towards the start site. (literal)

Prodotto di

• Institute of molecular genetics (IGM) (Istituto)

Autore CNR

• SILVANO RIVA (Persona)

Incoming links:

Prodotto

• Institute of molecular genetics (IGM) (Istituto)

Autore CNR di

• SILVANO RIVA (Persona)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• EMBO journal (Rivista)