Response to chemotherapy in gastric adenocarcinoma with diffusion-weighted MRI and 18 F-FDG-PET/CT: Correlation of apparent diffusion coefficient and partial volume corrected standardized uptake value with histological tumor regression grade (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Response to chemotherapy in gastric adenocarcinoma with diffusion-weighted MRI and 18 F-FDG-PET/CT: Correlation of apparent diffusion coefficient and partial volume corrected standardized uptake value with histological tumor regression grade (Articolo in rivista) (literal)

Anno

• 2014-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1002/jmri.24464 (literal)

Alternative label

• Francesco Giganti 1; Francesco De Cobelli 1; Carla Canevari 2,3; Elena Orsenigo 4; Francesca Gallivanone 3; Antonio Esposito 1; Isabella Castiglioni 3; Alessandro Ambrosi 5; Luca Albarello 6; Elena Mazza 7; Luigi Gianolli 2; Carlo Staudacher 4; Alessandro Del Maschio 1. (2014)
  Response to chemotherapy in gastric adenocarcinoma with diffusion-weighted MRI and 18 F-FDG-PET/CT: Correlation of apparent diffusion coefficient and partial volume corrected standardized uptake value with histological tumor regression grade
  in Journal of magnetic resonance imaging (Online)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Francesco Giganti 1; Francesco De Cobelli 1; Carla Canevari 2,3; Elena Orsenigo 4; Francesca Gallivanone 3; Antonio Esposito 1; Isabella Castiglioni 3; Alessandro Ambrosi 5; Luca Albarello 6; Elena Mazza 7; Luigi Gianolli 2; Carlo Staudacher 4; Alessandro Del Maschio 1. (literal)

Pagina inizio

• 1147 (literal)

Pagina fine

• 157 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#altreInformazioni

• Pubblicato on-line: 8 Novembre 2013. (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 40 (literal)

Rivista

• Journal of magnetic resonance imaging (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 5 (literal)

Note

• PubMe (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• 1. Department of Radiology and Center for Experimental Imaging, San Raffaele Scientific Institute, Vita-Salute University, Milan, Italy. 2. Department of Nuclear Medicine, San Raffaele Scientific Institute, Milan, Italy. 3. Institute of Molecular Bioimaging and Physiology, National Research Council, IBFM-CNR, Milan, Italy. 4. Department of Surgery, San Raffaele Scientific Institute, Vita-Salute University, Milan, Italy. 5. Neurobiology of Learning Unit, Vita-Salute San Raffaele University, Milan, Italy. 6 Pathology Unit, San Raffaele Scientific Institute, Milan, Italy. 7 Department of Oncology, San Raffaele Scientific Institute, Milan, Italy (literal)

Titolo

• Response to chemotherapy in gastric adenocarcinoma with diffusion-weighted MRI and 18 F-FDG-PET/CT: Correlation of apparent diffusion coefficient and partial volume corrected standardized uptake value with histological tumor regression grade (literal)

Abstract

• PURPOSE: To assess whether changes in diffusion-weighted MRI (DW-MRI) and 18 F-fluoro-2-deoxyglucose positron emission tomography/computed tomography (18 F-FDG PET/CT), correlate with treatment response to neoadjuvant therapy (NT), as expressed by tumor regression grade (TRG), from locally advanced gastric adenocarcinoma (GA). MATERIALS AND METHODS: Seventeen patients underwent both DW-MRI and 18 F-FDG-PET/CT scans before and after the end of NT. Apparent diffusion coefficient (ADC) and mean standardized uptake value (SUV) corrected for partial volume effect (PVC-SUVBW-mean ) were evaluated and compared with histopathological TRG. RESULTS: Pre- and post-NT and percentage changes for ADC and PVC-SUVBW-mean were assessed. Post-NT ADC and ?ADC showed a significant inverse correlation with TRG (r = -0.71; P = 0.0011 and r = -0.78; P = 0.00020, respectively) and significant differences in their mean values were found between responders (TRG 1-2-3) and nonresponders (TRG 4-5) (P = 0.0009; P = 0.000082, respectively). No correlations with TRG were found for pre-NT ADC and for all PVC-SUVBW-mean values as well as between ?ADC and ? PVC-SUVBW-mean . CONCLUSION: DW-MRI seems more accurate than 18 F-FDG-PET/CT and ADC modifications may represent a reproducible tool to assess tumor response for GA. (literal)

Prodotto di

• Institute of molecular bioimaging and physiology (IBFM) (Istituto)
• Imaging molecolare e proteogenomica (ME.P06.026.001) (Modulo)

Autore CNR

• FRANCESCA GALLIVANONE (Persona)
• CARLA CANEVARI (Persona)
• ISABELLA CASTIGLIONI (Persona)

Insieme di parole chiave

• Keywords of "Response to chemotherapy in gastric adenocarcinoma with diffusion-weighted MRI and 18 F-FDG-PET/CT: Correlation of apparent diffusion coefficient and partial volume corrected standardized uptake value with histological tumor regression grade" (Insieme di parole chiave)

Incoming links:

Prodotto

• Institute of molecular bioimaging and physiology (IBFM) (Istituto)
• Imaging molecolare e proteogenomica (ME.P06.026.001) (Modulo)

Autore CNR di

• ISABELLA CASTIGLIONI (Persona)
• CARLA CANEVARI (Persona)
• FRANCESCA GALLIVANONE (Persona)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Journal of magnetic resonance imaging (Rivista)

Insieme di parole chiave di

• Keywords of "Response to chemotherapy in gastric adenocarcinoma with diffusion-weighted MRI and 18 F-FDG-PET/CT: Correlation of apparent diffusion coefficient and partial volume corrected standardized uptake value with histological tumor regression grade" (Insieme di parole chiave)