Structural and compositional features of untranslated regions of eukaryotic mRNAs (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Structural and compositional features of untranslated regions of eukaryotic mRNAs (Articolo in rivista) (literal)

Anno

• 1997-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1016/S0378-1119(97)00407-1 (literal)

Alternative label

• Pesole G, Liuni S, Grillo G, Saccone C (1997)
  Structural and compositional features of untranslated regions of eukaryotic mRNAs
  in Gene (Amst.)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Pesole G, Liuni S, Grillo G, Saccone C (literal)

Pagina inizio

• 95 (literal)

Pagina fine

• 102 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 205 (literal)

Rivista

• Gene (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 1-2 (literal)

Note

• ISI Web of Science (WOS) (literal)
• SCImago (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Universitá della Basilicata, Potenza, Centro di Studio sui Mitocondri e Metabolismo Energetico,Bari, Universitá di Bari, Bari, Italy (literal)

Titolo

• Structural and compositional features of untranslated regions of eukaryotic mRNAs (literal)

Abstract

• The important role of 5' and 3' untranslated regions of eukaryotic mRNAs in gene regulation and expression is now widely accepted. In order to study the general structural and compositional features of these sequences we developed UTRdb, a specialized database of 5' and 3'-UTR sequences from seven different taxonomic groups of eukaryotic mRNAs cleaned of redundancy. The analysis of the UTR sequences contained in this database showed that 5'-UTR sequences, on average 200 nucleotides long, are 1.5-3 times shorter than the corresponding 3'-UTR sequences in the various taxonomic groups considered here. As to their compositional properties on average 5'-UTR sequences resulted in all cases GC richer than 3'-UTR sequences, and significant correlations were found between the GC content of 5' and 3'-UTR sequences and the GC content of the third silent codon positions of the corresponding protein coding genes. The dinucleotide analysis showed a differential depletion of CpG in vertebrate 5' and 3'-UTR, with 5'-UTR sequences being more CpG-rich, and a generalized depletion of TpA in both 5' and 3'-UTR was observed in all eukaryotic sequence collections. (literal)

Prodotto di

• Bioinformatica per la Genomica Funzionale e Comparata (SV.P18.004.001) (Modulo)

Autore CNR

• SABINO LIUNI (Persona)
• GIORGIO GRILLO (Unità di personale interno)

Incoming links:

Autore CNR di

• GIORGIO GRILLO (Unità di personale interno)
• SABINO LIUNI (Persona)

Prodotto

• Bioinformatica per la Genomica Funzionale e Comparata (SV.P18.004.001) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Gene (Rivista)