The untranslated regions of eukaryotic mRNAs: structure, function, evolution and bioinformatic tools for their analysis. (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• The untranslated regions of eukaryotic mRNAs: structure, function, evolution and bioinformatic tools for their analysis. (Articolo in rivista) (literal)

Anno

• 2000-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1093/bib/1.3.236 (literal)

Alternative label

• Pesole G, Grillo G, Larizza A, Liuni S. (2000)
  The untranslated regions of eukaryotic mRNAs: structure, function, evolution and bioinformatic tools for their analysis.
  in Briefings in bioinformatics
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Pesole G, Grillo G, Larizza A, Liuni S. (literal)

Pagina inizio

• 236 (literal)

Pagina fine

• 249 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 3 (literal)

Rivista

• Briefings in bioinformatics (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 3 (literal)

Note

• SCImago (literal)
• PubMe (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Università di Milano Università di Bari Centro Dtudi Mitocondri e Metabolismo Energetico, CNR-Bari (literal)

Titolo

• The untranslated regions of eukaryotic mRNAs: structure, function, evolution and bioinformatic tools for their analysis. (literal)

Abstract

• The crucial role of the non-coding portion of genomes is now widely acknowledged. In particular, mRNA untranslated regions are involved in many post-transcriptional regulatory pathways that control mRNA localisation, stability and translation efficiency. A review is given of the most recent research works on the functional characterisation of eukaryotic mRNA untranslated regions. In order to make possible a systematic and detailed sequence analysis of mRNA untranslated regions (UTRs), a non-redundant database of metazoan mRNA untranslated sequences annotated for the occurrence of specific functional elements, UTRdb, was devised. These elements, whose consensus structure has been devised on the basis of experimental assays and of comparative analyses, have been collected in the UTRsite database. A suitable pattern-matching software has been devised to search UTRsite patterns in user-submitted sequences, also assessing their statistical significance. Structural, compositional and evolutionary features of untranslated sequences of metazoan mRNAs have been investigated showing peculiar intra- and interspecific patterns. (literal)

Prodotto di

• Bioinformatica per la Genomica Funzionale e Comparata (SV.P18.004.001) (Modulo)

Autore CNR

• SABINO LIUNI (Persona)
• GIORGIO GRILLO (Unità di personale interno)

Incoming links:

Autore CNR di

• GIORGIO GRILLO (Unità di personale interno)
• SABINO LIUNI (Persona)

Prodotto

• Bioinformatica per la Genomica Funzionale e Comparata (SV.P18.004.001) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Briefings in bioinformatics (Rivista)