High resolution scintigraphy in diagnosis and radioguided surgery of diabetic foot osteomyelitis (Abstract/Poster in atti di convegno)

Type
Label
  • High resolution scintigraphy in diagnosis and radioguided surgery of diabetic foot osteomyelitis (Abstract/Poster in atti di convegno) (literal)
Anno
  • 2006-01-01T00:00:00+01:00 (literal)
Alternative label
  • Capriotti, G.;Di Santo, G.;D'Alessandria, C.;Lanzolla, T.;Di Stasio, F.;Anastasia, A.;Massari, R.;Trotta, C.;Soluri, A.;Scopinaro, F. (2006)
    High resolution scintigraphy in diagnosis and radioguided surgery of diabetic foot osteomyelitis
    in Congress EANM - European Association of Nuclear Medicine 2006, Atene, 30.9-4.10/2006
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Capriotti, G.;Di Santo, G.;D'Alessandria, C.;Lanzolla, T.;Di Stasio, F.;Anastasia, A.;Massari, R.;Trotta, C.;Soluri, A.;Scopinaro, F. (literal)
Pagina inizio
  • S356 (literal)
Pagina fine
  • S356 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali
  • 1 (literal)
Note
  • Poster (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • 1, 2, 3, 4, 5, 6, 9: University \"La Sapienza\", Rome, Italy; 6, 7, 8: Institute of Biomedical Engineering, ISIB-CNR, Rome, Rome, Italy. (literal)
Titolo
  • High resolution scintigraphy in diagnosis and radioguided surgery of diabetic foot osteomyelitis (literal)
Abstract
  • Aim: Osteomyelitis is a heavy complication of diabetic foot and its diagnosis requires an integrate approach, both for the clinicians and for the specialist imaging. Leukocytes scan (WBCS) plays a key role in the diagnosis of osteomyelitis. It is performed to reduce the number of amputation, to improve wound healing and to reduce the mortality of patients. The suboptimal spatial resolution of Anger cameras (AC) represents a limitation to achieve these goals. Some studies suggested the role of High Resolution Scintigraphy (HRS) in the diagnosis, radioguided surgery and biopsy of different diseases. Aim of present study is to verify if WBCS is able to improve the diagnosis of osteomyelitis and to help surgery with the use of an hand held High Resolution Detector (HRD),.Materials and Methods: 10 patients, mean age 64 yrs, with forefoot ulcers, were enrolled. In all patients planar X-ray, MRI and conventional 99mTc-HMPAO-WBCs were performed. 24h after administration of radiolabelled WBC, each patient was studied by HRS with HRD. The hand held HRD showed four inch2 FOV, 2 mm spatial resolution, 18% energy resolution. The patients underwent surgery or bone biopsy using HRS.Results: Three patients showed negative scan with both devices. They showed an ulcer without infection, debridement of lesion was sufficient to obtain healing (Table). Seven patients showed positive scan at AC without bone infection. HRD showed hot spots of radioactivity in the same patients. In four of them, the hot spot was bar-shaped. This bar-shaped radioactivity was considered as sign of osteomyelitis. One patient, with positive WBCs, refused surgery. Two patients, with positive scan and no sign of osteomyelitis at AC as well as at HRD underwent complete curettage of purulent inflammation using HRD during the surgical treatment. Two of the 4 patients showing infection at HRD were treated by amputation of the two distal phalanges of the toe because of osteomyelitis. The other patients underwent to radio-guided bone biopsy. Bone infection was confirmed by culture exam.Conclusions: HRD seems to be able to guide surgical treatment opening a new way in the therapy of infected foot. It is possible to assess if surgical removal of purulent inflammation is complete and to precisely guide biopsy or removal of the bone with osteomyelitis. (literal)
Prodotto di
Autore CNR
Insieme di parole chiave

Incoming links:


Prodotto
Autore CNR di
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi
Insieme di parole chiave di
data.CNR.it