Lisosan G, a powder of grain, does not interfer with the drug metabolizing enzymes and has a protective role on carbon tetrachloride-induced hepatotoxicity (Articolo in rivista)

Type
Label
  • Lisosan G, a powder of grain, does not interfer with the drug metabolizing enzymes and has a protective role on carbon tetrachloride-induced hepatotoxicity (Articolo in rivista) (literal)
Anno
  • 2007-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1007/s10529-007-9378-6 (literal)
Alternative label
  • Longo V.; Chirulli V.; Gervasi P. G.; Nencioni S.; Pellegrini M. (2007)
    Lisosan G, a powder of grain, does not interfer with the drug metabolizing enzymes and has a protective role on carbon tetrachloride-induced hepatotoxicity
    in Biotechnology letters
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Longo V.; Chirulli V.; Gervasi P. G.; Nencioni S.; Pellegrini M. (literal)
Pagina inizio
  • 1155 (literal)
Pagina fine
  • 1159 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 29 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note
  • In: Biotechnology Letters, vol. 29 pp. 1155 - 1159. Springer Science+Business Media B.V., 2007. (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali
  • 5 (literal)
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Laboratory of Pharmacogenetics and Drug Metabolism, Istituto di Fisiologia Clinica, CNR, Pisa Agrisan SRL, Larciano, PT, Italy (literal)
Titolo
  • Lisosan G, a powder of grain, does not interfer with the drug metabolizing enzymes and has a protective role on carbon tetrachloride-induced hepatotoxicity (literal)
Abstract
  • Lisosan G is a powder of grain registered as an alimentary integrator. The treatment of rats for 4 days with 0.5 g Lisosan G/kg had no effect on various drug metabolizing enzymes. Experiments in vitro showed that Lisosan G had radical scavenger activity. A confirmation of the antioxidative prop-erty of Lisosan G was also confirmed when it was administered in vivo to carbon tetrachloride (CCl4 )-intoxicated rats. The toxicity caused by CCl4 -treatment of rats was restored to the control levels when the rats were given Lisosan G for 4 days before CCl4 . Lisosan G thus does not interfer with drug metabolizing system but has antioxidant properties and protects against CCl4 -induced hepatotoxicity. (literal)
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