A Raman study of the copper(II) - Captopril system (Contributo in volume (capitolo o saggio))

Type
Label
  • A Raman study of the copper(II) - Captopril system (Contributo in volume (capitolo o saggio)) (literal)
Anno
  • 1999-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1007/978-94-011-4479-7_274 (literal)
Alternative label
  • Torreggiani, A; Tamba, M; Fini, G (1999)
    A Raman study of the copper(II) - Captopril system
    in Spectroscopy of Biological Molecules: New Directions, 1999
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Torreggiani, A; Tamba, M; Fini, G (literal)
Pagina inizio
  • 609 (literal)
Pagina fine
  • 610 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#titoloVolume
  • Spectroscopy of Biological Molecules: New Directions (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali
  • 2 (literal)
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Consiglio Nazionale delle Ricerche (CNR) (literal)
Titolo
  • A Raman study of the copper(II) - Captopril system (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#isbn
  • 0-7923-5847-3 (literal)
Abstract
  • Captopril (CpSH), a synthetic 3-mercapto-2 -methyl-propionyl derivative of L-proline, is a drug widely used in the treatment of arterial hypertension and congestive heart failure [1]. Since post-ischemic myocardial dysfunction is mediated, at least in part, by the generation of free radicals [2] and mobilises metal ions such as Cu(II) and Fe(III), which can catalyse the formation of reactive oxygen species (R.OS) able to produce oxidative damage [3], the beneficial effect of CpSH could be related to its scavenging ability towards radicals and free metals. In order to investigate the interaction of CpSH with Cu (II) ions, a Raman study of CpSH in the absence and in the presence of copper (II) was undertaken. (literal)
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