PET/CT in cancer research: from preclinical to clinical applications (Abstract in rivista)

Type

• Abstract in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• PET/CT in cancer research: from preclinical to clinical applications (Abstract in rivista) (literal)

Anno

• 2010-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1002/cmmi.368 (literal)

Alternative label

• Del Vecchio S, Zannetti A, Fonti R, Iommelli F, Pizzuti LM, Lettieri A, Salvatore M (2010)
  PET/CT in cancer research: from preclinical to clinical applications
  
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Del Vecchio S, Zannetti A, Fonti R, Iommelli F, Pizzuti LM, Lettieri A, Salvatore M (literal)

Pagina inizio

• 190 (literal)

Pagina fine

• 200 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 5 (literal)

Rivista

• Contrast media and molecular imaging (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 11 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 4 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Department of Biomorphological and Functional Sciences, University of Naples Federico II, Naples, Italy Istituto di Biostrutture e Bioimmagini, CNR - IBB, Napoli, Italy (literal)

Titolo

• PET/CT in cancer research: from preclinical to clinical applications (literal)

Abstract

• The identification of genetic and biochemical mechanisms underlying tumor growth and progression along with the unraveling of human genoma provided a plethora of new targets for cancer detection, treatment and monitoring. Simultaneously, the extraordinary development of a number of imaging technologies, including hybrid systems, allowed the visualization of biochemical, molecular and physiological aberrations linked to underlying mutations in a given tumor. In vivo evaluation of complex biological processes such as proliferation, apoptosis, angiogenesis, metastasis, gene expression, receptor-ligand interactions, transport of substrates and metabolism of nutrients in human cancers is feasible using PET/CT and radiolabeled molecular probes. Some of these compounds are in preclinical phases of evaluation whereas others have been already applied in clinical settings. Here we provide prominent examples on how some biological processes and target expression can be visualized by PET/CT in animal tumor models and cancer patients for the noninvasive detection of well-known markers of tumor aggressiveness, invasiveness and resistance to treatment and for the evaluation of tumor response to therapy. (literal)

Prodotto di

• Sviluppo di Approcci Diagnostici e Terapeutici Innovativi in Oncologia (ME.P03.001.004) (Modulo)
• Institute of biostructure and bioimaging (IBB) (Istituto)

Autore CNR

• ANTONELLA ZANNETTI (Unità di personale interno)
• ROSA FONTI (Unità di personale interno)
• SILVANA DEL VECCHIO (Unità di personale esterno)
• MARCO SALVATORE (Persona)
• LAURA MICOL PIZZUTI (Persona)
• FRANCESCA IOMMELLI (Unità di personale interno)

Incoming links:

Autore CNR di

• MARCO SALVATORE (Persona)
• ROSA FONTI (Unità di personale interno)
• ANTONELLA ZANNETTI (Unità di personale interno)
• FRANCESCA IOMMELLI (Unità di personale interno)
• LAURA MICOL PIZZUTI (Persona)
• SILVANA DEL VECCHIO (Unità di personale esterno)

Prodotto

• Institute of biostructure and bioimaging (IBB) (Istituto)
• Sviluppo di Approcci Diagnostici e Terapeutici Innovativi in Oncologia (ME.P03.001.004) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Contrast media and molecular imaging (Rivista)