Diode laser-assisted carotid bypass surgery: an experimental study with morphological and immunohistochemical evaluations (Articolo in rivista)

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Label
  • Diode laser-assisted carotid bypass surgery: an experimental study with morphological and immunohistochemical evaluations (Articolo in rivista) (literal)
Anno
  • 2006-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1227/01.NEU.0000249217.27214.EC (literal)
Alternative label
  • A.Puca, A.Albanese, G.Esposito, G.Maira, MD, B.Tirpakova, G.Rossi, A.Mannocci, R.Pini (2006)
    Diode laser-assisted carotid bypass surgery: an experimental study with morphological and immunohistochemical evaluations
    in Neurosurgery
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • A.Puca, A.Albanese, G.Esposito, G.Maira, MD, B.Tirpakova, G.Rossi, A.Mannocci, R.Pini (literal)
Pagina inizio
  • 1286 (literal)
Pagina fine
  • 1295 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 59 (literal)
Rivista
Note
  • PubMe (literal)
  • Scopu (literal)
  • ISI Web of Science (WOS) (literal)
  • Google Scholar (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • A.Puca, A.Albanese, G.Esposito, G.Maira, MD, B.Tirpakova,A.Mannocci, Univ.Cattolica Sacro Cuore, Roma G.Rossi, Dip. Scienze Veterinarie, Univ. Camerino R.Pini, IFAC (literal)
Titolo
  • Diode laser-assisted carotid bypass surgery: an experimental study with morphological and immunohistochemical evaluations (literal)
Abstract
  • OBJECTIVE: Conventional suturing methods of microvascular anastomosis are associated with various degrees of vascular wall damage that can lead to thrombosis and bypass occlusion. An experimental model of double end-to-side venous graft anastomosis on the common carotid artery was set up to compare conventional suturing methods with a low-power diode laser vascular welding technique. METHODS: The experiments were performed on 40 rabbits that underwent implantation of a 15-mm segment of jugular vein on the common carotid artery. The proximal end-to-side suture was performed by eight interrupted stitches; the distal suture, which was done using a laser welding technique, was supported by four stay sutures. The animals were evaluated after 2 days (n = 15), 9 days (n = 15), and 30 days (n = 10). The vascular segments were excised and subjected to histological, immunohistochemical, and ultrastructural evaluation. RESULTS: The average clamping time to perform both anastomoses was 35 minutes. At the end of the follow-up period, one case of complete occlusion was observed after 9 days and one case was observed after 30 days. Surgical observations and pathological evaluation indicated that adoption of the laser welding technique reduced operative time and bleeding. Histologically, a reduction of thrombosis, inflammation, myointimal hyperplasia, and dystrophic calcification was observed in laser-assisted anastomoses. A better preservation of the endothelium was also evident in laser-treated anastomoses. The observed differences were deemed statistically significant ( P= 0.05). CONCLUSION: Our study demonstrated the efficacy of diode laser welding in improving surgical techniques of high-flow bypass and in reducing the vascular wall damage observed with conventional methods. (literal)
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