http://www.cnr.it/ontology/cnr/individuo/prodotto/ID219162

Gray matter volume alterations related to trait dissociation in PTSD and traumatized controls. (Articolo in rivista)

Type

Articolo in rivista (Classe)
Prodotto della ricerca (Classe)

Label

Gray matter volume alterations related to trait dissociation in PTSD and traumatized controls. (Articolo in rivista) (literal)

Anno

2013-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

10.1111/acps.12026 (literal)

Alternative label

Nardo, D.; Hogberg, G.; Lanius, R.; Jacobsson, H.; Jonsson, C.; Hallstrom, T.; Pagani, Marco (2013)
Gray matter volume alterations related to trait dissociation in PTSD and traumatized controls.
in Acta psychiatrica Scandinavica
(literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

Nardo, D.; Hogberg, G.; Lanius, R.; Jacobsson, H.; Jonsson, C.; Hallstrom, T.; Pagani, Marco (literal)

Pagina inizio

222 (literal)

Pagina fine

233 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#altreInformazioni

DISCIPLINA DI RIFERIMENTO: Psychiatry; AREA DI VALUTAZIONE: 06 - Scienze mediche; CODIC EPUMA: /cnr.istc/2012-A0-029 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url

http://onlinelibrary.wiley.com/doi/10.1111/acps.12026/abstract (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

128 (literal)

Rivista

Acta psychiatrica Scandinavica (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

12 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

3 (literal)

Note

ISI Web of Science (WOS) (literal)
Scopu (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

CNR-ISTC, Roma5-Palestro (literal)

Titolo

Gray matter volume alterations related to trait dissociation in PTSD and traumatized controls. (literal)

Abstract

Objective: This study used voxel-based morphometry (VBM) to investigate brain structural alterations related to trait dissociation and its relationship with post-traumatic stress disorder (PTSD). Method: Thirty-two subjects either developing (N = 15) or non- developing (N = 17) PTSD underwent MRI scanning and were assessed with the Dissociative Experience Scale (DES), subscales for pathological (DES-T) and non-pathological trait (DES-A) dissociation, and other clinical measures. Gray matter volume (GMV) was analyzed using VBM as implemented in SPM. PTSD and non-PTSD subjects were compared to assess brain alterations related to PTSD pathology, whereas correlation analyses between dissociation measures and GMV were performed on the whole sample (N = 32), irrespective of PTSD diagnosis, to identify alterations related to trait dissociation. Results: As compared to traumatized controls, PTSD subjects showed reduced GMV in the prefrontal cortex, hippocampus and lingual gyrus. Correlations with dissociation measures (DES, DES-T, and DES-A) consistently showed increased GMV in the medial and lateral prefrontal, orbitofrontal, parahippocampal, temporal polar, and inferior parietal cortices. Conclusion: PTSD and dissociation seem to be associated with opposite volumetric patterns in the prefrontal cortex. Trait dissociation appears to involve increased GMV in prefrontal, paralimbic, and parietal cortices, with negligible differences between pathological and non-pathological dissociation. (literal)

Prodotto di

Autore CNR