An alternative approach in the structure-based predictions of thermodynamics of protein unfolding (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• An alternative approach in the structure-based predictions of thermodynamics of protein unfolding (Articolo in rivista) (literal)

Anno

• 1997-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1016/S0301-4622(97)00071-9 (literal)

Alternative label

• MILARDI D; C. LA ROSA; S. FASONE; D. GRASSO (1997)
  An alternative approach in the structure-based predictions of thermodynamics of protein unfolding
  in Biophysical chemistry (Print)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• MILARDI D; C. LA ROSA; S. FASONE; D. GRASSO (literal)

Pagina inizio

• 43 (literal)

Pagina fine

• 51 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 69 (literal)

Rivista

• Biophysical chemistry (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 9 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• MILARDI D; C. LA ROSA; S. FASONE; D. GRASSO, Dipartimento di Scienze Chimiche, Università degli studi di Catania. (literal)

Titolo

• An alternative approach in the structure-based predictions of thermodynamics of protein unfolding (literal)

Abstract

• A new approach for a first-order prediction of the thermodynamic properties of small globular proteins has been developed. The method put forward here has been shown to be successful in predicting, within acceptable margins of uncertainty, the denaturational heat capacity changes of a given protein if its amino acid composition is known. If compared with other models this method has the following advantages: (1) no details about the three-dimensional structure of the protein are required; (2) comparison with the thermodynamic properties of small model compounds is not necessary; (3) the temperature dependence of the denaturational heat capacity change is taken into account. Moreover, the equations developed have allowed us to point out the errors that can be made if the temperature-dependence of the denaturational heat capacity change is not taken into account in the calculation of the unfolding thermodynamic functions (literal)

Prodotto di

• Institute of biostructure and bioimaging (IBB) (Istituto)

Autore CNR

• DANILO MILARDI (Unità di personale interno)

Insieme di parole chiave

• Parole chiave di "An alternative approach in the structure-based predictions of thermodynamics of protein unfolding" (Insieme di parole chiave)

Incoming links:

Autore CNR di

• DANILO MILARDI (Unità di personale interno)

Prodotto

• Institute of biostructure and bioimaging (IBB) (Istituto)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Biophysical chemistry (Rivista)

Insieme di parole chiave di

• Parole chiave di "An alternative approach in the structure-based predictions of thermodynamics of protein unfolding" (Insieme di parole chiave)