HIGH MOBILITY GROUP HMGI(Y) PROTEIN EXPRESSION IN HUMAN COLORECTAL HYPERPLASTIC AND NEOPLASTIC DISEASES (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• HIGH MOBILITY GROUP HMGI(Y) PROTEIN EXPRESSION IN HUMAN COLORECTAL HYPERPLASTIC AND NEOPLASTIC DISEASES (Articolo in rivista) (literal)

Anno

• 2001-01-01T00:00:00+01:00 (literal)

Alternative label

• Gennaro CHIAPPETTA 1, Guidalberto MANFIOLETTI 2, Francesca PENTIMALLI 1, Nobutsugu ABE 3, Maurizio DI BONITO 1, Maria Teresa VENTO 1, Ada GIULIANO 1, Monica FEDELE 4, Giuseppe VIGLIETTO 1, Massimo SANTORO 4, Takashi WATANABE 3, Vincenzo GIANCOTTI 2 and Alfredo FUSCO 5 (2001)
  HIGH MOBILITY GROUP HMGI(Y) PROTEIN EXPRESSION IN HUMAN COLORECTAL HYPERPLASTIC AND NEOPLASTIC DISEASES
  in International journal of cancer (Print)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Gennaro CHIAPPETTA 1, Guidalberto MANFIOLETTI 2, Francesca PENTIMALLI 1, Nobutsugu ABE 3, Maurizio DI BONITO 1, Maria Teresa VENTO 1, Ada GIULIANO 1, Monica FEDELE 4, Giuseppe VIGLIETTO 1, Massimo SANTORO 4, Takashi WATANABE 3, Vincenzo GIANCOTTI 2 and Alfredo FUSCO 5 (literal)

Pagina inizio

• 147 (literal)

Pagina fine

• 151 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 91 (literal)

Rivista

• International journal of cancer (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• 2Dipartimento di Biochimica, Biofisica e Chimica delle Macromolecole, University of Trieste, Italy 3Dipartimento di Clinical Pathology, Kyorin University School of Medicine, Mitaka-City, Tokyo, Japan 4Dipartimento di Biologia e Patologia Cellulare e Molecolare, c/o Centro di Endocrinologia ed Oncologia Sperimentale del CNR, School of Medicine, University of Naples 'Federico II', Italy 5Department of Medicina Sperimentale e Clinica, School of Medicine, University of Catanzaro, Italy (literal)

Titolo

• HIGH MOBILITY GROUP HMGI(Y) PROTEIN EXPRESSION IN HUMAN COLORECTAL HYPERPLASTIC AND NEOPLASTIC DISEASES (literal)

Abstract

• HMGI(Y) proteins are overexpressed in experimental and human malignancies, including colon, prostate and thyroid carcinomas. To determine at which step of the carcinogenic process HMGI(Y) induction occurs, we analysed the expression of the HMGI(Y) proteins in hyperplastic, preneoplastic and neoplastic tissues of colorectal origin by immunohistochemistry. All the colorectal carcinomas were HMGI(Y)-positive, whereas no expression was detected in normal colon mucosa tissue. HMGI(Y) expression in adenomas was closely correlated with the degree of cellular atypia. Only 2 of the 18 non-neoplastic polyps tested were HMGI(Y)-positive. These data indicate that HMGI(Y) protein induction is associated with the early stages of neoplastic transformation of colon cells and only rarely with colon cell hyperproliferation. (literal)

Prodotto di

• Istituto per l'endocrinologia e l'oncologia \"Gaetano Salvatore\" (IEOS) (Istituto)
• Espressione genica e cancerogenesi tiroidea (SV.P15.001.001) (Modulo)

Autore CNR

• MASSIMO SANTORO (Persona)
• ALFREDO FUSCO (Unità di personale interno)
• MONICA FEDELE (Persona)

Incoming links:

Autore CNR di

• ALFREDO FUSCO (Unità di personale interno)
• MONICA FEDELE (Persona)
• MASSIMO SANTORO (Persona)

Prodotto

• Istituto per l'endocrinologia e l'oncologia \"Gaetano Salvatore\" (IEOS) (Istituto)
• Espressione genica e cancerogenesi tiroidea (SV.P15.001.001) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• International journal of cancer (Rivista)