Advances in targeting signal transduction pathways. (Articolo in rivista)
- Type
- Prodotto della ricerca (Classe)
- Articolo in rivista (Classe)
- Label
- Advances in targeting signal transduction pathways. (Articolo in rivista) (literal)
- Anno
- 2012-01-01T00:00:00+01:00 (literal)
- Alternative label
- McCubrey JA, Steelman LS, Chappell WH, Sun L, Davis NM, Abrams SL, Franklin RA, Cocco L, Evangelisti C, Chiarini F, Martelli AM, Libra M, Candido S, Ligresti G, Malaponte G, Mazzarino MC, Fagone P, Donia M, Nicoletti F, Polesel J, Talamini R, Bäsecke J, Mijatovic S, Maksimovic-Ivanic D, Michele M, Tafuri A, Duli?ska-Litewka J, Laidler P, D'Assoro AB, Drobot L, Umezawa D, Montalto G, Cervello M, Demidenko ZN. (2012)(literal)
Advances in targeting signal transduction pathways.
in Oncotarget
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- McCubrey JA, Steelman LS, Chappell WH, Sun L, Davis NM, Abrams SL, Franklin RA, Cocco L, Evangelisti C, Chiarini F, Martelli AM, Libra M, Candido S, Ligresti G, Malaponte G, Mazzarino MC, Fagone P, Donia M, Nicoletti F, Polesel J, Talamini R, Bäsecke J, Mijatovic S, Maksimovic-Ivanic D, Michele M, Tafuri A, Duli?ska-Litewka J, Laidler P, D'Assoro AB, Drobot L, Umezawa D, Montalto G, Cervello M, Demidenko ZN. (literal)
- Pagina inizio
- 1505 (literal)
- Pagina fine
- 1521 (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
- 3 (literal)
- Rivista
- Oncotarget (Rivista)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
- 12 (literal)
- Note
- ISI Web of Science (WOS) (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- 1 Department of Microbiology and Immunology, Brody School of Medicine at East Carolina University 2 Department of Communication Sciences and Disorders, College of Allied Health Sciences, East Carolina University, Greenville, North Carolina, USA 3 Dipartimento di Scienze Biomediche e Neuromotorie, Università di Bologna, Bologna, Italy 4 Institute of Molecular Genetics, National Research Council-IOR, Bologna, Italy 5 Department of Bio-Medical Sciences, University of Catania, Catania, Italy 6 Unit of Epidemiology and Biostatistics, Centro di Riferimento Oncologico, IRCCS, Aviano, Italy. 7 Department of Medicine, University of Göttingen, Göttingen, Germany 8 Department of Immunology, Instititue for Biological Research \"Sinisa Stankovic\", University of Belgrade, Belgrade, Serbia 9 Regina Elena National Cancer Institute, Rome, Italy 10 Sapienza, University of Rome, Department of Cellular Biotechnology and Hematology, Rome, Italy 11 Chair of Medical Biochemistry, Jagiellonian University Medical College, Kraków, Poland. 12 Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Rochester, MN, USA. 13 Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kyiv, Ukraine 14 Department of Molecular Target Medicine Screening, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan 15 Biomedical Department of Internal Medicine and Specialties, University of Palermo, Palermo, Italy 16 Consiglio Nazionale delle Ricerche, Istituto di Biomedicina e Immunologia Molecolare \"Alberto Monroy\", Palermo, Italy 17 Department of Cell Stress Biology, Roswell Park Cancer Institute, Buffalo, New York, USA (literal)
- Titolo
- Advances in targeting signal transduction pathways. (literal)
- Abstract
- Over the past few years, significant advances have occurred in both our understanding of the complexity of signal transduction pathways as well as the isolation of specific inhibitors which target key components in those pathways. Furthermore critical information is being accrued regarding how genetic mutations can affect the sensitivity of various types of patients to targeted therapy. Finally, genetic mechanisms responsible for the development of resistance after targeted therapy are being discovered which may allow the creation of alternative therapies to overcome resistance. This review will discuss some of the highlights over the past few years on the roles of key signaling pathways in various diseases, the targeting of signal transduction pathways and the genetic mechanisms governing sensitivity and resistance to targeted therapies. (literal)
- Prodotto di
- Autore CNR
- FRANCESCA CHIARINI (Unità di personale interno)
- MELCHIORRE CERVELLO (Persona)
- CAMILLA EVANGELISTI (Persona)
Incoming links:
- Autore CNR di
- MELCHIORRE CERVELLO (Persona)
- FRANCESCA CHIARINI (Unità di personale interno)
- CAMILLA EVANGELISTI (Persona)
- Prodotto
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi
- Oncotarget (Rivista)