A novel automated tool for calculating upper airways volume in patients with isolated Pierre Robin Sequence (IPRS) (Abstract/Poster in rivista)

Type
Label
  • A novel automated tool for calculating upper airways volume in patients with isolated Pierre Robin Sequence (IPRS) (Abstract/Poster in rivista) (literal)
Anno
  • 2012-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1594/ecr2012/C-1242 (literal)
Alternative label
  • S. SALERNO; C. GAGLIARDO; Carmelo MILITELLO; S. VITABILE; A. LO CASTO; M. MIDIRI. (2012)
    A novel automated tool for calculating upper airways volume in patients with isolated Pierre Robin Sequence (IPRS)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • S. SALERNO; C. GAGLIARDO; Carmelo MILITELLO; S. VITABILE; A. LO CASTO; M. MIDIRI. (literal)
Pagina inizio
  • C-1242 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 3 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
  • Suppl-1 (literal)
Note
  • Poster (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Università ddegli studi di Palermo. IBFM-CNR, UOS di Cefalù (PA) (literal)
Titolo
  • A novel automated tool for calculating upper airways volume in patients with isolated Pierre Robin Sequence (IPRS) (literal)
Abstract
  • Purpose: IPRS is characterized by cleft palate, micrognatia and frequently reduction or partial obstruction of the upper airways that may result in respiratory dysfunction needing surgical correction. To calculate precisely the upper airways reduction found in IPRS, an automated algorithm was applied to the images obtained with multi-detector computed tomography (MDCT). Methods and Materials: 5 patients with isolated PRS and severe respiratory impairment (3 males, 2 female, mean age 49,8 days) and 3 controls not affected by cranio-facial anomalies but similar for age, sex and weightwere submitted to cranio-facial and neck MDCT study (LightSpeed 16 GE Healthcare). The 5 patients with PRS underwent to MDCT examination for a preliminary evaluation of upper airways. Datasets obtained from the MDCT studies where processed with an homemade MatLAB script to automatically calculate the volume of upper airways and easily obtain three dimensional volume rendering (3D-VR) reconstructions with the aim to correlate the results with indication to surgery. Results: Our script uses a dynamic regions growing algorithm that exploits the different density of anatomical structures. This algorithm demonstrates a great performance in term of accuracy due to the intrinsic difference in density of the structures of interest and is even preferable to those algorithms based on global thresholding techniques. Conclusion: Our automated algorithm provide an accurate assessment of airways impairment, starting from MDCT images, and hopefully aid the decision making for the application of invasive treatment. (literal)
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