http://www.cnr.it/ontology/cnr/individuo/prodotto/ID200532
Effect of the mobile phase composition on the retention behaviour of diphenylsilica pre-coated plates (Articolo in rivista)
- Type
- Label
- Effect of the mobile phase composition on the retention behaviour of diphenylsilica pre-coated plates (Articolo in rivista) (literal)
- Anno
- 1986-01-01T00:00:00+01:00 (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
- 10.1016/S0021-9673(00)94853-2 (literal)
- Alternative label
Giuliana Grassini-Strazza, Isabella Nicoletti, Chiara. Polcaro, Anna Maria Girelli, Antonella Sanci (1986)
Effect of the mobile phase composition on the retention behaviour of diphenylsilica pre-coated plates
in Journal of chromatography (Print)
(literal)
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- Giuliana Grassini-Strazza, Isabella Nicoletti, Chiara. Polcaro, Anna Maria Girelli, Antonella Sanci (literal)
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- ISI Web of Science (WOS) (literal)
- Google Scholar (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- C.N.R. Istituto di Cromatografia, Area della Ricerca di Roma, Monterotondo Stazione,Rome (Italy); Dipartimento di Chimica. Università \"La Sapienza\", Roma (Italy) (literal)
- Titolo
- Effect of the mobile phase composition on the retention behaviour of diphenylsilica pre-coated plates (literal)
- Abstract
- The retention of some rifamycins and steroids on diphenyl bonded pre-coated silica gel plates, in relation to the mobile phase used, was examined by thin-layer chromatography. Neat organic solvents, non-aqueous and aqueous binary mixtures were tested as eluents. By comparison of retention data for rifamycins and steroids,
respectively, under non-aqueous and aqueous conditions, a dual retention mechanism on this diphenyl phase was found. Interactions with the residual silanol groups seemed to prevail when employing as mobile phase the more lipophilic solvents tested, such as chloroform or dichloromethane, whereas interactions with the aryl groups of the bonded phase prevailed when using high polarity alcohols or aqueous mixtures.
As a consequence, by changing the mobile phase, a large variation in selectivity with a concomitant change in retention order of the test compounds was observed. (literal)
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