Chiral capillary electrophoresis-electrospray mass spectrometry coupling using vancomycin as chiral selector (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Chiral capillary electrophoresis-electrospray mass spectrometry coupling using vancomycin as chiral selector (Articolo in rivista) (literal)

Anno

• 1998-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1016/S0021-9673(97)00978-3 (literal)

Alternative label

• FANALI S, DESIDERIO C, SCHULTE G, HEILTMEIER S, STRICKMAN D, CHANKVETADZE B, BLASCKE G (1998)
  Chiral capillary electrophoresis-electrospray mass spectrometry coupling using vancomycin as chiral selector
  in Journal of chromatography (Print)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• FANALI S, DESIDERIO C, SCHULTE G, HEILTMEIER S, STRICKMAN D, CHANKVETADZE B, BLASCKE G (literal)

Pagina inizio

• 69 (literal)

Pagina fine

• 76 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 800 (literal)

Rivista

• Journal of chromatography (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• IMC-CNR; IMC-CNR; University of Munster; University of Munster; University of Munster; University of Munster; University of Munster; (literal)

Titolo

• Chiral capillary electrophoresis-electrospray mass spectrometry coupling using vancomycin as chiral selector (literal)

Abstract

• Capillary electrophoresis-electrospray mass spectrometry coupling (CE- ESI-MS) using vancomycin (VC) as a chiral selector is described in this study. The self electrophoretic mobility of VC, as a positively charged chiral selector at low pH, allows us to avoid the contamination of the ion source of the ESI-MS with the chiral selector in a simple way. The usefulness of this technique is illustrated for the analysis of chiral anionic compounds of pharmaceutical importance. Additionally, examples of a stereospecific determination of ibuprofen and its phase 1 metabolites as well as etodolac and its metabolites in urine samples are described. The advantages of MS for peak identification, peak purity testing and for selective monitoring of overlapping peaks are demonstrated (literal)

Prodotto di

• Istituto di metodologie chimiche (IMC) (Istituto)
• Sviluppo di metodologie chimiche avanzate per lo studio di fenomeni delle scienze omiche (PM.P06.019.001) (Modulo)

Autore CNR

• SALVATORE FANALI (Unità di personale interno)
• CLAUDIA DESIDERIO (Unità di personale interno)

Incoming links:

Prodotto

• Istituto di metodologie chimiche (IMC) (Istituto)
• Sviluppo di metodologie chimiche avanzate per lo studio di fenomeni delle scienze omiche (PM.P06.019.001) (Modulo)

Autore CNR di

• SALVATORE FANALI (Unità di personale interno)
• CLAUDIA DESIDERIO (Unità di personale interno)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Journal of chromatography (Rivista)