Capillary electrochromatography and capillary electrochromatography- electrospray mass spectrometry for the separation of non-steroidal anti- inflammatory drugs (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Capillary electrochromatography and capillary electrochromatography- electrospray mass spectrometry for the separation of non-steroidal anti- inflammatory drugs (Articolo in rivista) (literal)

Anno

• 2000-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1016/S0021-9673(00)00658-0 (literal)

Alternative label

• DESIDERIO C, FANALI S (2000)
  Capillary electrochromatography and capillary electrochromatography- electrospray mass spectrometry for the separation of non-steroidal anti- inflammatory drugs
  in Journal of chromatography (Print)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• DESIDERIO C, FANALI S (literal)

Pagina inizio

• 123 (literal)

Pagina fine

• 132 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 895 (literal)

Rivista

• Journal of chromatography (Rivista)

Note

• PubMe (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• IMC-CNR; IMC-CNR; (literal)

Titolo

• Capillary electrochromatography and capillary electrochromatography- electrospray mass spectrometry for the separation of non-steroidal anti- inflammatory drugs (literal)

Abstract

• In this study capillary electrochromatography (CEC) was utilized for the separation of ten non-steroidal anti-inflammatory drugs (NSAIDs). Experiments were carried out in a commercially available CE instrument using a packed capillary with RP-18 silica particles where the stationary phase completely filled the capillary. The mobile phase consisted of a mixture of ammonium formate buffer pH 2.5 and acetonitrile. Selectivity and resolution were studied changing the pH and the concentration of the buffer, the acetonitrile content mobile phase and the capillary temperature. The optimum experimental conditions for CEC separation of the studied drug mixture were found using 50 mM ammonium formate pH 2.5-acetonitrile (40:60) at 25°C. The CEC capillary was coupled to an electrospray mass spectrometer for the characterization of the NSAIDs. A mobile phase composed by the same buffer but with a higher concentration of acetonitrile (90%) was used in order to speed up the separation of analytes. (C) 2000 Elsevier Science B.V. (literal)

Prodotto di

• Sviluppo di metodologie chimiche avanzate per lo studio di fenomeni delle scienze omiche (PM.P06.019.001) (Modulo)
• Istituto di metodologie chimiche (IMC) (Istituto)

Autore CNR

• CLAUDIA DESIDERIO (Unità di personale interno)
• SALVATORE FANALI (Unità di personale interno)

Incoming links:

Prodotto

• Istituto di metodologie chimiche (IMC) (Istituto)
• Sviluppo di metodologie chimiche avanzate per lo studio di fenomeni delle scienze omiche (PM.P06.019.001) (Modulo)

Autore CNR di

• SALVATORE FANALI (Unità di personale interno)
• CLAUDIA DESIDERIO (Unità di personale interno)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Journal of chromatography (Rivista)