Insights on the susceptibility of plant pathogenic fungi to phenazine-1- carboxylic acid and its chemical derivatives (Articolo in rivista)

Type
Label
  • Insights on the susceptibility of plant pathogenic fungi to phenazine-1- carboxylic acid and its chemical derivatives (Articolo in rivista) (literal)
Anno
  • 2012-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1080/14786419.2012.696257 (literal)
Alternative label
  • Puopolo G, Masi M, Raio A, Andolfi A, Zoina A, Cimmino A, Evidente A. (2012)
    Insights on the susceptibility of plant pathogenic fungi to phenazine-1- carboxylic acid and its chemical derivatives
    in Natural product research (Print); Taylor and Francis, Abingdon (Regno Unito)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Puopolo G, Masi M, Raio A, Andolfi A, Zoina A, Cimmino A, Evidente A. (literal)
Rivista
Note
  • PubMe (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • 1) Puopolo G, Zoina A; 2) Masi M, Andolfi A,, Cimmino A, Evidente A. 1) Dipartimento di Arboricoltura, Botanica e Patologia Vegetale, Universitá di Napoli Federico II, Via Università 100, 80055 Portici, Italy 2) Dipartimento di Scienze del Suolo, della Pianta, dell'Ambiente e delle Produzioni Animali, Università di Napoli Federico II, Via Università 100, 80055 Portici, Italy (literal)
Titolo
  • Insights on the susceptibility of plant pathogenic fungi to phenazine-1- carboxylic acid and its chemical derivatives (literal)
Abstract
  • Pseudomonas chlororaphis subsp. aureofaciens strain M71 produced two phenazine compounds as main secondary metabolites. These metabolites were identified as phenazine-1-carboxylic acid (PCA) and 2-hydroxyphenazine (2-OH P). In this study, the spectrum of the activity of PCA and 2-OH P was evaluated against a group of crop and forestal plant pathogenic fungi by an agar plate bioassay. PCA was active against most of the tested plant pathogens, while 2-OH P slightly inhibited a few fungal species. Furthermore, four semisynthesised derivatives of PCA (phenazine-1-carboxymethyl, phenazine-1-carboxamide, phenazine-1-hydroxymethyl and phenazine-1-acetoxymethyl) were assayed for their antifungal activity against 11 phytopathogenic species. Results showed that the carboxyl group is a structural feature important for the antifungal activity of PCA. Since the activity of phenazine-1-carboxymethyl and phenazine-1-carboxamide, the two more lipophilic and reversible PCA derivatives remained substantially unaltered compared with PCA. (literal)
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