http://www.cnr.it/ontology/cnr/individuo/prodotto/ID188161

Distinguishing the co-ancestries of haplogroup G Y-chromosomes in the populations of Europe and the Caucasus. (Articolo in rivista)

Type

Articolo in rivista (Classe)
Prodotto della ricerca (Classe)

Label

Distinguishing the co-ancestries of haplogroup G Y-chromosomes in the populations of Europe and the Caucasus. (Articolo in rivista) (literal)

Anno

2012-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

10.1038/ejhg.2012.86 (literal)

Alternative label

Rootsi S, Myres NM, Lin AA, Järve M, King RJ, Kutuev I, Cabrera VM, Khusnutdinova EK, Varendi K, Sahakyan H, Behar D, Khusainova R, Balanovsky O, Balanovska E, Rudan P, Yepiskoposyan L, Bahmanimehr A, Farjadian S, Kushniarevich A, Herrera RJ, Grugni V, Battaglia V, Nici C, Crobu F, Karacanak S, Hooshiar Kashani B, Houshmand M, Sanati HM, Toncheva D, Lisa A, Semino O, Chiaroni J, Di Cristofaro J, Villems R, Kivisild T, Underhill PA. (2012)
Distinguishing the co-ancestries of haplogroup G Y-chromosomes in the populations of Europe and the Caucasus.
in European journal of human genetics; NATURE PUBLISHING GROUP,, LONDON (Regno Unito)
(literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

Rootsi S, Myres NM, Lin AA, Järve M, King RJ, Kutuev I, Cabrera VM, Khusnutdinova EK, Varendi K, Sahakyan H, Behar D, Khusainova R, Balanovsky O, Balanovska E, Rudan P, Yepiskoposyan L, Bahmanimehr A, Farjadian S, Kushniarevich A, Herrera RJ, Grugni V, Battaglia V, Nici C, Crobu F, Karacanak S, Hooshiar Kashani B, Houshmand M, Sanati HM, Toncheva D, Lisa A, Semino O, Chiaroni J, Di Cristofaro J, Villems R, Kivisild T, Underhill PA. (literal)

Pagina inizio

1275 (literal)

Pagina fine

1282 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

20 (literal)

Rivista

European journal of human genetics (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

12 (literal)

Note

ISI Web of Science (WOS) (literal)
Scopu (literal)
PubMe (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

Evolutionary Biology Group, Estonian Biocentre, Tartu, Estonia; Ancestry.com, Provo, UT, USA; Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA; Department of Evolutionary Biology, Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia; Institute of Biochemistry and Genetics, Ufa Research Center, Russian Academy of Sciences, Ufa, Russia; Departamento de Genética, Facultad de Biología, Universidad de La Laguna, Tenerife, Spain; Human Genetics Group, Institute of Molecular Biology, Academy of Sciences of Armenia, Yerevan, Armenia; Research Centre for Medical Genetics, Russian Academy of Medical Sciences, Moscow, Russia; Institute for Anthropological Research, Zagreb, Croatia; Immunology department, Allergy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran; Department of Human and Molecular Genetics, College of Medicine, Florida International University, Miami, FL, USA; Dipartimento di Biologia e Biotecnologie 'L. Spallanzani', Università di Pavia, Pavia, Italy; Department of Medical Genetics, Medical University of Sofia, Sofia, Bulgaria; National Institute of Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran; Istituto di Genetica Molecolare - Centro Nazionale delle Ricerche, Pavia, Italy; Centro Interdipartimentale 'Studi di Genere', Università di Pavia, Pavia, Italy; Unite Mixte de Recherche 6578, Centre National de la Recherche Scientifique, and Etablissement Français du Sang, Biocultural Anthropology, Medical Faculty, Université de la Méditerranée, Marseille, France; Estonian Academy of Sciences, Tallinn, Estonia; Department of Biological Anthropology, University of Cambridge, Cambridge, UK; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA (literal)

Titolo

Distinguishing the co-ancestries of haplogroup G Y-chromosomes in the populations of Europe and the Caucasus. (literal)

Abstract

Haplogroup G, together with J2 clades, has been associated with the spread of agriculture, especially in the European context. However, interpretations based on simple haplogroup frequency clines do not recognize underlying patterns of genetic diversification. Although progress has been recently made in resolving the haplogroup G phylogeny, a comprehensive survey of the geographic distribution patterns of the significant sub-clades of this haplogroup has not been conducted yet. Here we present the haplogroup frequency distribution and STR variation of 16 informative G sub-clades by evaluating 1472 haplogroup G chromosomes belonging to 98 populations ranging from Europe to Pakistan. Although no basal G-M201* chromosomes were detected in our data set, the homeland of this haplogroup has been estimated to be somewhere nearby eastern Anatolia, Armenia or western Iran, the only areas characterized by the co-presence of deep basal branches as well as the occurrence of high sub-haplogroup diversity. The P303 SNP defines the most frequent and widespread G sub-haplogroup. However, its sub-clades have more localized distribution with the U1-defined branch largely restricted to Near/Middle Eastern and the Caucasus, whereas L497 lineages essentially occur in Europe where they likely originated. In contrast, the only U1 representative in Europe is the G-M527 lineage whose distribution pattern is consistent with regions of Greek colonization. No clinal patterns were detected suggesting that the distributions are rather indicative of isolation by distance and demographic complexities. (literal)

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