Integration of Hybrid Single-Photon Emission Computed Tomography/Computed Tomography in the Preoperative Assessment of Sentinel Node in Patients With Cervical and Endometrial Cancer Our Experience and Literature Review (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Integration of Hybrid Single-Photon Emission Computed Tomography/Computed Tomography in the Preoperative Assessment of Sentinel Node in Patients With Cervical and Endometrial Cancer Our Experience and Literature Review (Articolo in rivista) (literal)

Anno

• 2012-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1097/IGC.0b013e318253496f (literal)

Alternative label

• Alessandro Buda; Federica Elisei; Maurizio Arosio; Carlotta Dolci; Mauro Signorelli; Patrizia Perego; Daniela Giuliani; Dario Recalcati; Giorgio Cattoretti; Rodolfo Milani; Cristina Messa. (2012)
  Integration of Hybrid Single-Photon Emission Computed Tomography/Computed Tomography in the Preoperative Assessment of Sentinel Node in Patients With Cervical and Endometrial Cancer Our Experience and Literature Review
  in International journal of gynecological cancer
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Alessandro Buda; Federica Elisei; Maurizio Arosio; Carlotta Dolci; Mauro Signorelli; Patrizia Perego; Daniela Giuliani; Dario Recalcati; Giorgio Cattoretti; Rodolfo Milani; Cristina Messa. (literal)

Pagina inizio

• 830 (literal)

Pagina fine

• 835 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 22 (literal)

Rivista

• International journal of gynecological cancer (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 5 (literal)

Note

• PubMe (literal)
• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Univ Milano Bicocca, Dept Obstet & Gynecol, San Gerardo Hosp, Bioimaging Mol Ctr, Monza, Italy Univ Milano Bicocca, Dept Nucl Med, San Gerardo Hosp, Bioimaging Mol Ctr, Monza, Italy Univ Milano Bicocca, Dept Pathol, San Gerardo Hosp, Monza, Italy Univ Milano Bicocca, Fdn Tecnomed, Monza, Italy IBFM CNR, Segrate (MI), Italy (literal)

Titolo

• Integration of Hybrid Single-Photon Emission Computed Tomography/Computed Tomography in the Preoperative Assessment of Sentinel Node in Patients With Cervical and Endometrial Cancer Our Experience and Literature Review (literal)

Abstract

• OBJECTIVE: The purpose of this study was to assess whether there is an additional value of single-photon emission computed tomography/computed tomography (SPECT/CT) over lymphoscintigraphy (LSG) alone for sentinel node (SN) mapping in endometrial and cervical cancer. METHODS: Ten women with clinically cervical stage IA2 to stage IB1 and 25 women with stage I endometrial cancer underwent preoperative LSG for SN mapping. Technetium Tc 99m albumin nanocolloid was injected submucosally at 4 points of the cervix. Patients underwent SPECT/CT emission-transmission study at least 3 hours after standard planar images. Methylene blue was injected into the cervix just before surgery under general anesthesia. All patients underwent hysterectomy, bilateral salpingo-oophorectomy, and radical regional nodal dissection. Hot and/or blue nodes were labeled as SNs. RESULTS: Conventional planar imaging detection rate was 50%, whereas the detection rate of at least one SN with SPECT/CT was 91% (32/35); bilateral detection was achieved in 7 (39%) of 18 women in planar and in 17 (53%) of 32 women in SPECT/CT imaging, respectively. Bilateral detection was achieved in 57% of women (20/35). Sentinel nodes were located in external and internal iliac nodes (66%), obturator nodes (5%), internal iliac nodes (11%), common iliac nodes (9%), and presacral nodes (9%). Lymph node involvement was identified in 5 patients (14%). Sentinel node correctly predicted lymph node involvement in all node-positive patients. Sentinel node sensitivity and negative predictive value of SPECT/CT were 100%. CONCLUSIONS: Single photon emission computed tomography/computed tomography seems to improve intraoperative identification of SNs and provides additional useful information about the anatomic location of SNs compared to planar LSG in cervical and endometrial cancer. (literal)

Prodotto di

• Institute of molecular bioimaging and physiology (IBFM) (Istituto)
• Imaging molecolare in oncologia (ME.P06.006.003) (Modulo)

Autore CNR

• MARIA CRISTINA MESSA (Unità di personale esterno)

Insieme di parole chiave

• Keywords of "Integration of Hybrid Single-Photon Emission Computed Tomography/Computed Tomography in the Preoperative Assessment of Sentinel Node in Patients With Cervical and Endometrial Cancer Our Experience and Literature Review" (Insieme di parole chiave)

Incoming links:

Autore CNR di

• MARIA CRISTINA MESSA (Unità di personale esterno)

Prodotto

• Institute of molecular bioimaging and physiology (IBFM) (Istituto)
• Imaging molecolare in oncologia (ME.P06.006.003) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• International journal of gynecological cancer (Rivista)

Insieme di parole chiave di

• Keywords of "Integration of Hybrid Single-Photon Emission Computed Tomography/Computed Tomography in the Preoperative Assessment of Sentinel Node in Patients With Cervical and Endometrial Cancer Our Experience and Literature Review" (Insieme di parole chiave)