Choline pivaloyl esters improve in rats cognitive and memory performances impaired by scopolamine treatment or lesions of the nucleus basalis of Meynert (Articolo in rivista)

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  • Choline pivaloyl esters improve in rats cognitive and memory performances impaired by scopolamine treatment or lesions of the nucleus basalis of Meynert (Articolo in rivista) (literal)
Anno
  • 2004-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1016/j.neulet.2003.11.054 (literal)
Alternative label
  • Vincenzo Rispolia; Domenicantonio Rotirotia; Vincenzo Carellib; Felice Liberatoreb; Luigi Scipioneb; Rosario Marrac; Gianfabio Giorgionid; Antonio Di Stefanod (2004)
    Choline pivaloyl esters improve in rats cognitive and memory performances impaired by scopolamine treatment or lesions of the nucleus basalis of Meynert
    in Neuroscience letters (Print)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Vincenzo Rispolia; Domenicantonio Rotirotia; Vincenzo Carellib; Felice Liberatoreb; Luigi Scipioneb; Rosario Marrac; Gianfabio Giorgionid; Antonio Di Stefanod (literal)
Pagina inizio
  • 199 (literal)
Pagina fine
  • 202 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 356 (literal)
Rivista
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Department of 'Scienze Farmacobiologiche', University of Catanzaro 'Magna Græcia', Complesso 'Nin?` Barbieri', 88021 Roccelletta di Borgia (CZ), Italy; Department of 'Studi di Chimica e Tecnologia delle Sostanze Biologicamente Attive', University of Rome 'La Sapienza', Piazzale Aldo Moro,5, 00185 Rome, Italy; CNR Institute of 'Scienze Neurologiche', 88021 Roccelletta di Borgia, Catanzaro, Italy; Department of 'Scienze Chimiche', University of Camerino, Via S. Agostino, 1, 62032 Camerino, Italy (literal)
Titolo
  • Choline pivaloyl esters improve in rats cognitive and memory performances impaired by scopolamine treatment or lesions of the nucleus basalis of Meynert (literal)
Abstract
  • The effects of two choline pivaloyl esters, [2-(2,2-dimethylpropionyloxy)ethyl]trimethylammonium iodide (1) and [2-(2,2-dimethylpropionyloxy)ethyl]trimethylammonium 2,2-dimethylpropionate (2), on learning and memory impairments induced in rats by scopolamine or lesions of nucleus basalis magnocellularis (NBM) have been evaluated by object recognition and Morris water maze tests in comparison with Tacrine (THA). Both 1 and 2 restored discrimination in object recognition test for assessing working-episodic memory and improved spatial memory in scopolamine or NBM-lesioned rats as well. The positive effects produced by 1 and 2 on cognitive and memory deficits were well comparable with those evoked by THA, used as reference compound. (C) 2003 Elsevier Ireland Ltd. All rights reserved. (literal)
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