Assessing social skills in on fine cooperative learning (Contributo in atti di convegno)

Type
Label
  • Assessing social skills in on fine cooperative learning (Contributo in atti di convegno) (literal)
Anno
  • 2005-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1002/jms.909 (literal)
Alternative label
  • Basilico, F ; Sauerwein, W; Pozzi, F ; Wattig, A; Moss, R; Mauri, PL (2005)
    Assessing social skills in on fine cooperative learning
    in 23rd Informal Meeting on Mass Spectrometry, Fiera di Primiero, ITALY, MAY 15-19, 2005
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Basilico, F ; Sauerwein, W; Pozzi, F ; Wattig, A; Moss, R; Mauri, PL (literal)
Pagina inizio
  • 1546 (literal)
Pagina fine
  • 1549 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 40 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
  • 12 (literal)
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • 1. Ist Tecnol Biomed, Milan, Italy 2. Univ Klinikum Essen, Strahlenklin, D-45122 Essen, Germany 3. NRG, Nucl Res & Consultancy Grp, Petten, Netherlands (literal)
Titolo
  • Assessing social skills in on fine cooperative learning (literal)
Abstract
  • Boron neutron capture therapy (BNCT) is a promising binary treatment for cancer. BNCT is based on the ability of the nonradioactive isotope B-10 to capture, with a very high probability, thermal neutrons. This nuclear reaction results in two particles (an alpha and a lithium nucleus). The particles have a high biological effectiveness, which is limited in tissue to approximately the diameter of one cell. If the reaction can be limited to a tumor cell, the physical characteristic opens up the possibility to selectively destroy cancer cells, while sparing the surrounding healthy tissue. Quality control of B-10-containing compounds and their distribution at present are very important, and different analytical methods have been developed, such as time-of-flight secondary ion mass spectrometry (TOF-SIMS), electron energy loss spectrometry (EELS), prompt gamma analysis and inductively coupled plasma-optical emission spectrometry (ICP-OES). These methods allow the analyses of B-10, but it is not possible to characterize the specific molecular compounds containing B-10. For this reason, we propose a fast and quantitative method that permits the determination of closo-undecahydro-1-mercaptododecaborate (BSH) and (10)boron-phenylalanine (BPA) and their eventual metabolites. In particular, B-10-containing compounds are detected by means of flow-injection electrospray tandem mass spectrometry (FI/ESI-MS/MS). This approach allows the identification of Boron compounds, BSH and BPA, using tandem mass spectrometry, and quantitative analysis is also possible (c.v. +/- 4.7%; n = 5; linear range 10-10000 ng/ml). Furthermore, B-10-containing compounds were detected in actual biological sample (urine and plasma, diluted 10000- and 1000-fold, respectively) injecting a small volume (1 mu l) of diluted samples. (literal)
Autore CNR
Insieme di parole chiave

Incoming links:


Autore CNR di
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi
Insieme di parole chiave di
data.CNR.it