http://www.cnr.it/ontology/cnr/individuo/prodotto/ID186269
IMPRECO: Distributed prediction of protein complexes (Articolo in rivista)
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- Label
- IMPRECO: Distributed prediction of protein complexes (Articolo in rivista) (literal)
- Anno
- 2010-01-01T00:00:00+01:00 (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
- 10.1016/j.future.2009.08.001 (literal)
- Alternative label
M. Cannataro; Pietro H. Guzzi; P. Veltri (2010)
IMPRECO: Distributed prediction of protein complexes
in Future generation computer systems; ELSEVIER SCIENCE BV, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS, AMSTERDAM (Paesi Bassi)
(literal)
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- M. Cannataro; Pietro H. Guzzi; P. Veltri (literal)
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- http://www.sciencedirect.com/science/article/pii/S0167739X09001113 (literal)
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- Mario Cannataro, Pietro H. Guzzi ?, Pierangelo Veltri
Bioinformatics Laboratory, Department of Experimental Medicine and Clinic, University Magna Graecia, Viale Europa, 88100 Catanzaro, Italy (literal)
- Titolo
- IMPRECO: Distributed prediction of protein complexes (literal)
- Abstract
- Proteins interact among themselves, and different interactions form a very huge number of possible combinations representable as protein-to-protein interaction (PPI) networks that are mapped into graph structures. Proteincomplexes are a subset of mutually interacting proteins. Starting from a PPI network, proteincomplexes may be extracted by using computational methods. The paper proposes a new complexes meta-predictor which is capable of predicting proteincomplexes by integrating the results of different predictors. It is based on a distributed architecture that wraps predictor as web/grid services that is built on top of the grid infrastructure. The proposed meta-predictor first invokes different available predictors wrapped as services in a parallel way, then integrates their results using graph analysis, and finally evaluates the predicted results by comparing them against external databases storing experimentally determined protein complexes. (literal)
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