http://www.cnr.it/ontology/cnr/individuo/prodotto/ID186073
Preparation of Shell Cross-Linked Nano-Objects from Hybrid-Peptide Block Copolymers (Articolo in rivista)
- Type
- Label
- Preparation of Shell Cross-Linked Nano-Objects from Hybrid-Peptide Block Copolymers (Articolo in rivista) (literal)
- Anno
- 2005-01-01T00:00:00+01:00 (literal)
- Alternative label
R. Rodiguez-Hernandez, J. Babin, B. Zappone, S. Lecommandoux (2005)
Preparation of Shell Cross-Linked Nano-Objects from Hybrid-Peptide Block Copolymers
in Biomacromolecules; ACS, American chemical society, Washington, DC (Stati Uniti d'America)
(literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- R. Rodiguez-Hernandez, J. Babin, B. Zappone, S. Lecommandoux (literal)
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- Rivista
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- ISI Web of Science (WOS) (literal)
- PubMed (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- 1) Laboratoire de Chimie des Polymeres Organiques (LCPO-UMR5629), ENSCPB-University Bordeaux 1,
16, Av. Pey Berland, 33607 Pessac Cedex, France
2) Centre de Recherche Paul Pascal, CNRS-University Bordeaux 1, Av. Schweitzer, 33600 Pessac Cedex, France (literal)
- Titolo
- Preparation of Shell Cross-Linked Nano-Objects from Hybrid-Peptide Block Copolymers (literal)
- Abstract
- Supramolecular structures formed by self-assembly of diblock copolymers in solution are stable over restricted
environmental conditions: concentration, temperature, pH, or ion strength among others. To enlarge their
domain of application, it appears necessary to develop stabilization strategies. We report here different
strategies to stabilize the shell of micelles formed by self-assembly of amphiphilic polydiene-b-polypeptide
diblock copolymers. For this purpose, covalent bonds can be formed between either amine or carboxylic
acid groups distributed along the soluble peptide block and a cross-linking agent that contains respectively
aldehyde or amine functions. Shell stabilization affords systems with unique properties that combine three
main advantages: shape persistence, control of the porosity, and stimuli-responsive behavior. The covalent
capture of such macromolecular objects has been studied by light scattering, AFM, and conductimetry
measurements. (literal)
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