Incidence of invasive cervical cancer and direct costs associated with its management in Italy (Articolo in rivista)

Type
Label
  • Incidence of invasive cervical cancer and direct costs associated with its management in Italy (Articolo in rivista) (literal)
Anno
  • 2009-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1700/422.5001 (literal)
Alternative label
  • Ricciardi A; Largeron N; Giorgi Rossi P; Raffaele M; Cohet C; Federici A; Palazzo F. (2009)
    Incidence of invasive cervical cancer and direct costs associated with its management in Italy
    in Tumori (Testo stamp.))
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Ricciardi A; Largeron N; Giorgi Rossi P; Raffaele M; Cohet C; Federici A; Palazzo F. (literal)
Pagina inizio
  • 146 (literal)
Pagina fine
  • 152 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 95 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali
  • 7 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
  • 2 (literal)
Note
  • ISI Web of Science (WOS) (literal)
  • Scopu (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Agency for Public Health, Lazio Region, Rome, Italy; Sanofi Pasteur MSD, Lyon Cedex 07, France; INRCA, Department of Medical Oncology, Rome; National Research Council, Institute of Research on Population and Social Policies, Rome, Italy (literal)
Titolo
  • Incidence of invasive cervical cancer and direct costs associated with its management in Italy (literal)
Abstract
  • Aim and background. Cervical cancer is the second most common cancer in European women aged 15-44 years. The aim of this study was to estimate the direct cost of managing invasive cervical cancer in Italy. Methods. Data from the Italian Network of Cancer Registries were used to estimate the annual number of new cervical cancer cases. To assess the management costs, a typical management pathway for each FIGO (Fédération Internationale de Gynécologie et d'Obstétrique) cervical cancer stage was derived frompublished guidelines. Data fromtheModena Cancer Registry were used to estimate the proportion of patients by FIGO stage. This algorithm was combined with tariffs for outpatient and inpatient procedures to obtain a mean cost for each FIGO stage. Results.An estimated 2,927 new cases of cervical cancer occurred in Italy in 2005 (crude incidence 9.7/100,000; world age-standardized incidence 6.0/100,000). The estimated numbers of newcases by FIGO stagewere: FIGO I, 1,927; FIGO II, 556; FIGO III, 259; and FIGO IV, 185. Costs for themost frequent procedures were estimated as: EUR 6,041 for radical hysterectomy or other surgery; EUR 4,901 for radio-chemotherapy; EUR 1,588 for brachytherapy; and EUR 3,795 for palliative chemotherapy.Meanmanagement costs for incident cases (including 10 years of follow-up) were estimated at: FIGO I, EUR 6,024; FIGO II, EUR 10,572; FIGOIII,EUR11,367; FIGOIV,EUR8707; andEUR5,854 for the terminal phase (1month). The total directmanagement cost was estimated at EUR 28.3million per year. Conclusions. This is one of the first studies to estimate the direct cost of treating patients newly diagnosed with invasive cervical cancer in Italy. Although according to current management pathways real treatment costs are likely to be underestimated, this information is necessary to design evidence-based vaccination policies able to harmonize primary and secondary prevention of cervical cancer. (literal)
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