http://www.cnr.it/ontology/cnr/individuo/prodotto/ID179183
Controlling enantioselectivity in chiral capillary electrophoresis with inclusion-complexation (Articolo in rivista)
- Type
- Label
- Controlling enantioselectivity in chiral capillary electrophoresis with inclusion-complexation (Articolo in rivista) (literal)
- Anno
- 1997-01-01T00:00:00+01:00 (literal)
- Alternative label
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Salvatore Fanali (literal)
- Pagina inizio
- Pagina fine
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
- Rivista
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- Istituto di Metodologie Chimiche (literal)
- Titolo
- Controlling enantioselectivity in chiral capillary electrophoresis with inclusion-complexation (literal)
- Abstract
- The separation of chiral compounds is of key importance in different fields of application, e.g., pharmaceutical, industrial,
forensic, biological, clinical etc. Capillary electrophoresis (CE) is a powerful analytical method applied in chiral analysis and
inclusion-complexation is one of the most frequently used mechanism to improve the selectivity of the enantiomeric
separation. Cyclodextrins and their derivatives or modified crown-ethers have been successfully applied in CE for the
enantiomeric separation of a wide number of analytes. This review surveys the separation of enantiomers by CE when chiral
selectors, forming inclusion-complexation, are used. The control of enantioselectivity can be done carefully by considering
several experimental parameters such as chiral selector type and concentration, pH, ionic strength and concentration of the
background electrolyte, electroosmotic flow, organic modifier etc. The review presents a list of the latest separation of
enantiomers by CE where inclusion-complexation plays a key role in the stereoselective separation mechanism. Ó 1997
Elsevier Science B.V. (literal)
- Prodotto di
- Autore CNR
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