Microarray glass slides coated with block copolymer brushes obtained by reversible addition chain-transfer polymerization (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Microarray glass slides coated with block copolymer brushes obtained by reversible addition chain-transfer polymerization (Articolo in rivista) (literal)

Anno

• 2006-01-01T00:00:00+01:00 (literal)

Alternative label

• Pirri G.; Chiari M.; Damin F. MEO A. (2006)
  Microarray glass slides coated with block copolymer brushes obtained by reversible addition chain-transfer polymerization
  in Analytical chemistry (Wash.)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Pirri G.; Chiari M.; Damin F. MEO A. (literal)

Pagina inizio

• 3118 (literal)

Pagina fine

• 3124 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 78 (literal)

Rivista

• Analytical chemistry (Rivista)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Istituto di Chimica del Riconoscimento Molecolare CNR (literal)

Titolo

• Microarray glass slides coated with block copolymer brushes obtained by reversible addition chain-transfer polymerization (literal)

Abstract

• The reversible addition-fragmentation chain-transfer polymerization was used to prepare microarray slides grafted with polymer brushes for DNA-based applications. Block copolymer brushes of N,N-dimethylacrylamide (DMA) and glycidyl methacrylate (GMA), poly(DMA-b-GMA) were prepared by extending living poly(dimethylacrylamide) chains. The functional surface was used as a substrate for oligonucleotide hybridization experiments. The results were compared to those provided by glass slides coated by a self-assembled monolayer made of (3-glycidyloxypropyl)trimethoxysilane. Surfaces coated with block polymer brushes bearing oxirane groups are more efficient as substrates for oligonucleotide, hybridization than surfaces coated with nonpolymeric self-assembled monolayers containing the same functional group. The high probe grafting density and hybridization efficiency achieved with this polymeric coating reveal the importance of the block architecture to ensure good accessibility of the immobilized probe. The new surface was characterized by static angle measurements and diffuse reflectance FT-IR spectroscopy on a silica model system. (literal)

Prodotto di

• Istituto di chimica del riconoscimento molecolare (ICRM) (Istituto)
• Sintesi di materiali funzionali e sviluppo di sistemi analitici miniaturizzati (PM.P06.003.001) (Modulo)

Autore CNR

• MARCELLA CHIARI (Unità di personale interno)
• FRANCESCO DAMIN (Unità di personale esterno)
• GIOVANNA PIRRI (Unità di personale esterno)

Incoming links:

Prodotto

• Istituto di chimica del riconoscimento molecolare (ICRM) (Istituto)
• Sintesi di materiali funzionali e sviluppo di sistemi analitici miniaturizzati (PM.P06.003.001) (Modulo)

Autore CNR di

• MARCELLA CHIARI (Unità di personale interno)
• FRANCESCO DAMIN (Unità di personale esterno)
• GIOVANNA PIRRI (Unità di personale esterno)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Analytical chemistry (Rivista)