http://www.cnr.it/ontology/cnr/individuo/prodotto/ID172674

Atopy influences exhaled nitric oxide levels in healthy schoolchildren (Abstract in rivista)

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Atopy influences exhaled nitric oxide levels in healthy schoolchildren (Abstract in rivista) (literal)

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F Cibella; G Cuttitta;S La Grutta; G Viegi; ML Lospalluti; C Uasuf; M Melis; S Marino (2007)
Atopy influences exhaled nitric oxide levels in healthy schoolchildren
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F Cibella; G Cuttitta;S La Grutta; G Viegi; ML Lospalluti; C Uasuf; M Melis; S Marino (literal)

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Pubblicato su: ERS Meeting, 2007. Eur Respir J 2007;30 (suppl 51). In: European Respiratory Journal, vol. 30 (51) pp. non disponibili -. 17esimo ERS Annual Congress. European Respiratory Society, 2007. (literal)

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Aim of the study was to investigate the factors influencing eNO levels in a sample of schoolchildren with or without respiratory disease. We studied 767 schoolchildren, aged l0-16years,randomly selected from l6 junior high schools of Palermo,Italy.A respiratory qu estionnaire was fulfilled. Spirometry,skin tests,and oral eNO measures were performed. Among subjects, 13.7% reported symptoms of bronchial asthma(A),25.7% had rhinitis(R),and 60.6% were asymptomatic(C).The FEV1/FVC% was 88.8%(6.1 SD)in A ,90.5%(6.0)in R and 90.9%(6.6)in C (p0.002).Atopics were 5 5.2%i n A, 43.9% in R, and 35.9%in C. Among atopic subjects, 194(62.4%)had a positive skin test for dermatophagoides. Median exhaled NO(and interquartile range)was 19.5 ppb(12.7-35.0)in atopics and 13.9 ppb(10.6-18.4)in non atopics(p0.0001).Among asymptomatics,atopics had significantly higher eNO than non atopics(p0.0001).Doctor diagnosed asthma was asociated to increased eNO values only in atopic subjects(p (literal)

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Istituto di Biomedicina e Immunologia Molecolare del Consiglio Nazionale delle Ricerche, Palermo Istituto di Fisiologia Clinica del Consiglio Nazionale delle Ricerche, Pisa (literal)

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