Grid methodology for identifying co-regulated genes and transcription factor binding sites (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Grid methodology for identifying co-regulated genes and transcription factor binding sites (Articolo in rivista) (literal)

Anno

• 2007-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1109/TNB.2007.897470 (literal)

Alternative label

• Van der Wath, Elizabeth; Moutsianas, Loukas; van der Wath, Richard; Visagie, Alet; Milanesi, Luciano; Lio, Pietro (2007)
  Grid methodology for identifying co-regulated genes and transcription factor binding sites
  in IEEE transactions on nanobioscience
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Van der Wath, Elizabeth; Moutsianas, Loukas; van der Wath, Richard; Visagie, Alet; Milanesi, Luciano; Lio, Pietro (literal)

Pagina inizio

• 162 (literal)

Pagina fine

• 167 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 6 (literal)

Rivista

• IEEE transactions on nanobioscience (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 6 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 2 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Istituto Tecnologie Biomediche (ITB) Consiglio Nazionale delle Ricerche (CNR), University of Cambridge; University of Oxford; University of Pretoria; (literal)

Titolo

• Grid methodology for identifying co-regulated genes and transcription factor binding sites (literal)

Abstract

• The identification of the genes that are coordinately regulated is an important and challenging task of bioinformatics and represents a first step in the elucidation of the topology of transcriptional networks. We first compare the performances, in a grid setting, of the Markov clustering algorithm with respect to the k-means using microarray test data sets. The gene expression information of the clustered genes can be used to annotate transcription binding sites upstream co-regulated genes. The methodology uses a regression model that relates gene expression levels to the matching scores of nucleotide patterns allowing us to identify DNA-binding sites from a collection of noncoding DNA sequences from co-regulated genes. Here we discuss extending the approach to multiple species exploiting the grid framework. (literal)

Prodotto di

• Applicazioni della Bioinformatica e Neuroinformatica al GRID computing (PM.P06.010.001) (Modulo)
• Modellistica Molecolare e GRID computing (INT.P02.011.001) (Modulo)
• Bioinformatica in Biomedicina (ME.P06.027.001) (Modulo)

Autore CNR

• LUCIANO MILANESI (Persona)

Insieme di parole chiave

• Keywords of "Grid methodology for identifying co-regulated genes and transcription factor binding sites" (Insieme di parole chiave)

Incoming links:

Autore CNR di

• LUCIANO MILANESI (Persona)

Prodotto

• Bioinformatica in Biomedicina (ME.P06.027.001) (Modulo)
• Modellistica Molecolare e GRID computing (INT.P02.011.001) (Modulo)
• Applicazioni della Bioinformatica e Neuroinformatica al GRID computing (PM.P06.010.001) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• IEEE transactions on nanobioscience (Rivista)

Insieme di parole chiave di

• Keywords of "Grid methodology for identifying co-regulated genes and transcription factor binding sites" (Insieme di parole chiave)