Comparison of colonoscopy and fecal occult blood testing as a first-line screening of colonic lesions in patients with newly diagnosed acromegaly (Articolo in rivista)

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Label
  • Comparison of colonoscopy and fecal occult blood testing as a first-line screening of colonic lesions in patients with newly diagnosed acromegaly (Articolo in rivista) (literal)
Anno
  • 2010-01-01T00:00:00+01:00 (literal)
Alternative label
  • Bogazzi F.; Lombardi M.; Scattina I.; Urbani C.; Marciano E.; Costa A.; Pepe P.; Rossi G.; Martino E. (2010)
    Comparison of colonoscopy and fecal occult blood testing as a first-line screening of colonic lesions in patients with newly diagnosed acromegaly
    in Journal of endocrinological investigation (Testo stamp.)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Bogazzi F.; Lombardi M.; Scattina I.; Urbani C.; Marciano E.; Costa A.; Pepe P.; Rossi G.; Martino E. (literal)
Pagina inizio
  • 530 (literal)
Pagina fine
  • 533 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 33 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note
  • In: Journal of Endocrinological Investigation, vol. 33 pp. 530 - 533. KEDITRICE KURTIS, 2010. (literal)
Note
  • ubMe (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Department of Endocrinology and Metabolism, University of Pisa, DEPARTMENT OF ONCOLOGY UNIVERSITY OF PISA, CNR-IFC, Pisa (literal)
Titolo
  • Comparison of colonoscopy and fecal occult blood testing as a first-line screening of colonic lesions in patients with newly diagnosed acromegaly (literal)
Abstract
  • Patients with acromegaly have frequently colonic neoplasms; however, how acromegalic patients should be screened for colonic lesions is still unsettled. Aims: To compare fecal occult blood testing (FOBT) and colonoscopy in the screening program of patients with acromegaly. Design: Colonoscopy and FOBT were performed at the first diagnosis of acromegaly. Setting: Tertiary University center. Patients: Eighty-five consecutive patients with untreated active acromegaly submitted to colonoscopy and FOBT. Results: FOBT, which was positive in 16 (18.8%) out of 85 patients, identified 2 patients withcolonic adenocarcinoma and 2 with adenoma; the remaining 12 patients had no detectable colonic lesions. Colonoscopy revealed colonic lesions in 29 patients: 3 (3.5%) cancers, 11 (12.9%) adenomas, and 15 (17.6%) hyperplastic polyps. The remaining 56 acromegalic patients had no detectable lesions. A patient with cancer and 9 patients with adenoma were missed if screened only by FOBT. Conclusions: Colonoscopy is superior to FOBT in detecting colonic lesions at the first diagnosis of acromegaly. (literal)
  • Patients with acromegaly have frequently colonic neoplasms; however, how acromegalic patients should be screened for colonic lesions is still unsettled. Aims: To compare fecal occult blood testing (FOBT) and colonoscopy in the screening program of patients with acromegaly. Design: Colonoscopy and FOBT were performed at the first diagnosis of acromegaly. Setting: Tertiary University center. Patients: Eighty-five consecutive patients with untreated active acromegaly submitted to colonoscopy and FOBT. Results: FOBT, which was positive in 16 (18.8%) out of 85 patients, identified 2 patients withcolonic adenocarcinoma and 2 with adenoma; the remaining 12 patients had no detectable colonic lesions. Colonoscopy revealed colonic lesions in 29 patients: 3 (3.5%) cancers, 11 (12.9%) adenomas, and 15 (17.6%) hyperplastic polyps. The remaining 56 acromegalic patients had no detectable lesions. A patient with cancer and 9 patients with adenoma were missed if screened only by FOBT. Conclusions: Colonoscopy is superior to FOBT in detecting colonic lesions at the first diagnosis of acromegaly. (literal)
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