http://www.cnr.it/ontology/cnr/individuo/prodotto/ID167630

Consequences of Helicobacter pylori infection in children. (Articolo in rivista)

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Consequences of Helicobacter pylori infection in children. (Articolo in rivista) (literal)

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Alternative label

Pacifico L.1) Anania C.1) Osborn J.F.2) Ferraro F.1) Chiesa C.3) (2010)
Consequences of Helicobacter pylori infection in children.
in World Journal of Gastroenterology; WJG Press, Beijing (Cina)
(literal)

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1) Dept Pediatrics,Sapienza University of Rome, Italy 2) Dept Public Heallth Sciences and Infectious Diseases, Sapienza University of Rome, Italy 3) Institute of Neurobiology and Molecular Medicine,National Research Council,Rome, Italy. (literal)

Titolo

Abstract

Although evidence is emerging that the prevalence of Helicobacter pylori (H. pylori) is declining in all age groups, the understanding of its disease spectrum continues to evolve. If untreated, H. pylori infection is lifelong. Although H. pylori typically colonizes the human stomach for many decades without adverse consequences, children infected with H. pylori can manifest gastrointestinal diseases. Controversy persists regarding testing (and treating) for H. pylori infection in children with recurrent abdominal pain, chronic idiopathic thrombocytopenia, and poor growth. There is evidence of the role of H. pylori in childhood iron deficiency anemia, but the results are not conclusive. The possibility of an inverse relationship between H. pylori and gastroesophageal reflux disease, as well as childhood asthma, remains a controversial question. A better understanding of the H. pylori disease spectrum in childhood should lead to clearer recommendations about testing for and treating H. pylori infection in children who are more likely to develop clinical sequelae. (literal)

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