Interaction between the DNA model base 9-ethylguanine and a group of ruthenium polypyridyl complexes: Kinetics and conformational temperature dependence (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Interaction between the DNA model base 9-ethylguanine and a group of ruthenium polypyridyl complexes: Kinetics and conformational temperature dependence (Articolo in rivista) (literal)

Anno

• 2007-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1021/ic070092u (literal)

Alternative label

• Corral E.; Hotze A.C.G.; Magistrato A.; Reedijk J. (2007)
  Interaction between the DNA model base 9-ethylguanine and a group of ruthenium polypyridyl complexes: Kinetics and conformational temperature dependence
  in Inorganic chemistry
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Corral E.; Hotze A.C.G.; Magistrato A.; Reedijk J. (literal)

Pagina inizio

• 6715 (literal)

Pagina fine

• 6722 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 46 (literal)

Rivista

• Inorganic chemistry (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 16 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Leiden Univ, Leiden Inst Chem, Gorlaeus Labs, NL-2300 RA Leiden, Netherlands; INFM, CNR Democritos, Trieste, Italy; Scuola Int Super Studi Avanzati, Trieste, Italy (literal)

Titolo

• Interaction between the DNA model base 9-ethylguanine and a group of ruthenium polypyridyl complexes: Kinetics and conformational temperature dependence (literal)

Abstract

• The binding capability of three ruthenium polypyridyl compounds of structural formula [Ru(apy)(tpy)Ln-](ClO4)((2-n)) [1a-c; apy = 2,2'-azobis(pyridine), tpy = 2,2':6',2 ''-terpyridine, L = Cl, H2O, CH3CN] to a fragment of DNA was studied. The interaction between each of these complexes and the DNA model base 9-ethylguanine (9-EtGua) was followed by means of H-1 NMR studies. Density functional theory calculations were carried out to explore the preferential ways of coordination between the ruthenium complexes and guanine. The ruthenium-9-EtGua adduct formed was isolated and fully characterized using different techniques. A variable-temperature H-1 NMR experiment was carried out that showed that while the 9-EtGua fragment was rotating fast at high temperature, a loss of symmetry was suffered by the model base adduct as the temperature was lowered, indicating restricted rotation of the guanine residue. (literal)

Prodotto di

• Modelizzazione molecolare di sistemi biologici (MD.P06.026.001) (Modulo)

Autore CNR

• ALESSANDRA MAGISTRATO (Unità di personale interno)

Insieme di parole chiave

• Keywords of "Interaction between the DNA model base 9-ethylguanine and a group of ruthenium polypyridyl complexes: Kinetics and conformational temperature dependence" (Insieme di parole chiave)

Incoming links:

Autore CNR di

• ALESSANDRA MAGISTRATO (Unità di personale interno)

Prodotto

• Modelizzazione molecolare di sistemi biologici (MD.P06.026.001) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Inorganic chemistry (Rivista)

Insieme di parole chiave di

• Keywords of "Interaction between the DNA model base 9-ethylguanine and a group of ruthenium polypyridyl complexes: Kinetics and conformational temperature dependence" (Insieme di parole chiave)