Copper (II) complexes of oligopeptides containing aspartyl and glutamyl residues. Potentiometric and spectroscopic studies. (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Copper (II) complexes of oligopeptides containing aspartyl and glutamyl residues. Potentiometric and spectroscopic studies. (Articolo in rivista) (literal)

Anno

• 2005-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1016/j.jinorgbio.2005.04.009 (literal)

Alternative label

• C. Kállay; K. Várnagy; G. Micera; D. Sanna; I. Sóvágó (2005)
  Copper (II) complexes of oligopeptides containing aspartyl and glutamyl residues. Potentiometric and spectroscopic studies.
  in Journal of inorganic biochemistry
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• C. Kállay; K. Várnagy; G. Micera; D. Sanna; I. Sóvágó (literal)

Pagina inizio

• 1514 (literal)

Pagina fine

• 1525 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url

• http://www.sciencedirect.com/science/article/pii/S016201340500108X (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 99 (literal)

Rivista

• Journal of inorganic biochemistry (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 7 (literal)

Note

• Scopu (literal)
• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Department of Inorganic and Analytical Chemistry, University of Debrecen, P.O. Box 21, H-4010 Debrecen, Hungary Department of Chemistry, University of Sassari, via Vienna 2, I-07100 Sassari, Italy Istituto CNR di Chimica Biomolecolare, Sezione di Sassari, Traversa La Crucca, 3 - Regione Baldinca, I-07040 Li Punti - Sassari, Italy (literal)

Titolo

• Copper (II) complexes of oligopeptides containing aspartyl and glutamyl residues. Potentiometric and spectroscopic studies. (literal)

Abstract

• Copper(II) complexes of di-, tri- and tetra-peptides built up from Asp and/or Glu residues were studied by potentiometric and various spectroscopic techniques including UV-visible, circular dichroism and electron paramagnetic resonance measurements. The ligands contain two to five carboxylate functions and it generally results in the enhanced metal binding ability of the ligands, which is especially true for the oligopeptides of aspartic acid. In the case of peptides containing aspartyl residue in the N-terminal position the stability enhancement is reflected in the equilibrium data of the species [CuL] containing the (NH2, b-COO-)-coordination mode in a 6-membered chelate. In the case of AspAsp and AspAspAsp the (NH2, N-, b-COO-) and (NH2, N-, N-, b-COO-)-coordination modes will be favoured, which contain (5,6) and (5,5,6)-joined chelate ring systems, respectively. The outstanding stability of the latter binding mode and the high negative charge of the corresponding species suppresses the metal ion coordination of the third amide function of AspAspAspAsp. It is also important to note that the presence of side chain carboxylate functions results in the formation of carboxylato-bridged polynuclear complexes in medium pH range. The extent of oligomerisation can be significantly enhanced by the increase of concentration and by the decrease of temperature. (literal)

Prodotto di

• Caratterizzazione di complessi metallici formati da proteine coinvolte in patologie correlate al disordine conformazionale proteico. (PM.P01.004.002) (Modulo)
• Istituto di chimica biomolecolare (ICB) (Istituto)

Autore CNR

• DANIELE SANNA (Persona)

Insieme di parole chiave

• Keywords of "Copper (II) complexes of oligopeptides containing aspartyl and glutamyl residues. Potentiometric and spectroscopic studies." (Insieme di parole chiave)

Incoming links:

Autore CNR di

• DANIELE SANNA (Persona)

Prodotto

• Istituto di chimica biomolecolare (ICB) (Istituto)
• Caratterizzazione di complessi metallici formati da proteine coinvolte in patologie correlate al disordine conformazionale proteico. (PM.P01.004.002) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Journal of inorganic biochemistry (Rivista)

Insieme di parole chiave di

• Keywords of "Copper (II) complexes of oligopeptides containing aspartyl and glutamyl residues. Potentiometric and spectroscopic studies." (Insieme di parole chiave)