Synthesis, conformational analysis, and spectroscopic characterization of peptides based on Daf, the first rigid transition-metal receptor, cyclic C-alpha, alpha-disubstituted glycine (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Synthesis, conformational analysis, and spectroscopic characterization of peptides based on Daf, the first rigid transition-metal receptor, cyclic C-alpha, alpha-disubstituted glycine (Articolo in rivista) (literal)

Anno

• 2002-01-01T00:00:00+01:00 (literal)

Alternative label

• Peggion C., Crisma M., Formaggio F., Toniolo C., Wright K., Wakselman M., Mazaleyrat J.P. (2002)
  Synthesis, conformational analysis, and spectroscopic characterization of peptides based on Daf, the first rigid transition-metal receptor, cyclic C-alpha, alpha-disubstituted glycine
  in Biopolymers (Print)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Peggion C., Crisma M., Formaggio F., Toniolo C., Wright K., Wakselman M., Mazaleyrat J.P. (literal)

Pagina inizio

• 314 (literal)

Pagina fine

• 324 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 63 (literal)

Rivista

• Biopolymers (Rivista)

Note

• ISI Web of Science (WOS) (literal)

Titolo

• Synthesis, conformational analysis, and spectroscopic characterization of peptides based on Daf, the first rigid transition-metal receptor, cyclic C-alpha, alpha-disubstituted glycine (literal)

Abstract

• Three series of terminally protected model oligopeptides to the nonamer level, based on 9-amino-4,5-diazafluorene-9-carboxylic acid (Daf) and either Gly, L-Ala, or Aib were synthesized. The molecular structures of two derivatives and one tripeptide were determined in the crystal state by X-ray diffraction. The solution preferred conformations of these peptides were assessed by FT-IR and NMR techniques. A spectroscopic (uv absorption, fluorescence, CD) of this novel heteroaromatic C-alpha-alpha-disubstituted glycine is also reported. Preliminary conformational data and membrane activity are reported for an analog of the lipopeptaibol antibiotic trichogin GA IV in which a Daf residue was incorporated at position 1 (replacing the original Aib). (literal)

Prodotto di

• Institute of biomolecular chemistry (ICB) (Istituto)

Incoming links:

Prodotto

• Institute of biomolecular chemistry (ICB) (Istituto)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Biopolymers (Rivista)