Spatial distribution of spin-labeled trichogin GA IV in the Gram-positive bacterial cell membrane determined from PELDOR data (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Spatial distribution of spin-labeled trichogin GA IV in the Gram-positive bacterial cell membrane determined from PELDOR data (Articolo in rivista) (literal)

Anno

• 2002-01-01T00:00:00+01:00 (literal)

Alternative label

• Milov A.D., Samoilova R.I., Tsvetkov Yu.D., Gusev V.A., Formaggio F., Crisma M., Toniolo C., Raap J. (2002)
  Spatial distribution of spin-labeled trichogin GA IV in the Gram-positive bacterial cell membrane determined from PELDOR data
  in Applied magnetic resonance
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Milov A.D., Samoilova R.I., Tsvetkov Yu.D., Gusev V.A., Formaggio F., Crisma M., Toniolo C., Raap J. (literal)

Pagina inizio

• 81 (literal)

Pagina fine

• 95 (literal)

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• Citazioni WOS: 10 Impact Factor 2002: 0.673 Coautore (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 23 (literal)

Rivista

• Applied magnetic resonance (Rivista)

Note

• ISI Web of Science (WOS) (literal)

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• Institute of Chemical Kinetics and Combustion, Russian Academy of Science Novosibirsk, Russian Federation; Institute of Mathematics, Russian Academy of Science Novosibirsk, Russian Federation; Biopolymer Research Center, CNR, Department of Organic Chemistry, University of Padova, 35131 Padova, Italy; Leiden Institute of Chemistry, Gorlaeus Laboratories, Leiden University, Leiden, The Netherlands (literal)

Titolo

• Spatial distribution of spin-labeled trichogin GA IV in the Gram-positive bacterial cell membrane determined from PELDOR data (literal)

Abstract

• Trichogin GA IV is one of the shortest acyclic linear polypeptide antibiotics of fungal origin, characterized by the presence of three alpha-amino isobutyric acid residues, an N-octanoyl group and an amino alcohol at the C terminus. Its antibiotic activity is generally thought to be based on its self-assembling and membrane-modifying properties. The technique of double electron-electron resonance in electron spin echo is used to study the spatial distribution of spin-labeled [TOAC-4]trichogin GA IV analog bound to the cell membrane of the Gram-positive bacterium Micrococcus luteus. The intermolecular dipole-dipole spin-spin interaction of TOAC spin labels has been experimentally studied at 77 K in glassy dispersions of the spherical cell particles. It is shown that the nonaggregated peptide molecules are distributed at the cytoplasmic membrane. Two possible distribution models are proposed: (i) the peptide molecules are randomly distributed on both inner and outer membrane surfaces with a distance between the surfaces of 7 run, (ii) the molecules are randomly distributed in a layer up to 2.4 mn from the external surface of the membrane. (literal)

Prodotto di

• Institute of biomolecular chemistry (ICB) (Istituto)

Autore CNR

• MARCO CRISMA (Unità di personale interno)

Incoming links:

Autore CNR di

• MARCO CRISMA (Unità di personale interno)

Prodotto

• Institute of biomolecular chemistry (ICB) (Istituto)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Applied magnetic resonance (Rivista)