Single-photon emission computed tomography after nitrate administration predicts cardiac events in patients with previous myocardial infarction and left ventricular dysfunction (Articolo in rivista)

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  • Single-photon emission computed tomography after nitrate administration predicts cardiac events in patients with previous myocardial infarction and left ventricular dysfunction (Articolo in rivista) (literal)
Anno
  • 2007-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1016/j.cardfail.2007.05.007 (literal)
Alternative label
  • Acampa, Wanda; Evangelista, Laura; Sorrentino, Anna Rita; Petretta, Mario; Luongo, Luca; Cuocolo, Alberto (2007)
    Single-photon emission computed tomography after nitrate administration predicts cardiac events in patients with previous myocardial infarction and left ventricular dysfunction
    in Journal of cardiac failure (Print)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Acampa, Wanda; Evangelista, Laura; Sorrentino, Anna Rita; Petretta, Mario; Luongo, Luca; Cuocolo, Alberto (literal)
Pagina inizio
  • 765 (literal)
Pagina fine
  • 768 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 13 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali
  • 4 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
  • 9 (literal)
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • University of Naples Federico II; University of Naples Federico II; University of Naples Federico II; SDN Fdn (literal)
Titolo
  • Single-photon emission computed tomography after nitrate administration predicts cardiac events in patients with previous myocardial infarction and left ventricular dysfunction (literal)
Abstract
  • Background: We determined the impact of viability assessment by nitrate single-photon emission computed tomography (SPECT) on cardiac events during long-term follow-up in patients with previous myocardial infarction, impaired left ventricular (LV) function, and no evidence of inducible ischemia. (literal)
  • Methods and Results: Sestamibi SPECT after nitrate was performed in 93 medically treated patients with previous myocardial infarction and LV dysfunction (ejection fraction <40%). Viability was defined as >= 2 dysfunctional segments with preserved tracer uptake (>= 55% of peak activity). Cardiac events were cardiac death, myocardial infarction and late revascularization. Sixty-five (70%) patients had evidence of viability at SPECT, whereas 28 (30%) did not. During 43 +/- 24 months of follow-up, cardiac events occurred in 32 (49%) of the 65 patients with viability and in 5 (18%) of the 28 patients without (P < .001). At Cox analysis, only the extent of viability predicted cardiac events (hazards ratio 1.6, 95% CI 1.3-2.0, global chi-square 14.3, P < .0001). Cumulative probability of event-free survival was 22% in patients with viability and 81% in those without (P < .001). (literal)
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