Dynamics of prefrontal and cingulate activity during a reward-based logical deduction task. (Articolo in rivista)

Type
Label
  • Dynamics of prefrontal and cingulate activity during a reward-based logical deduction task. (Articolo in rivista) (literal)
Anno
  • 2007-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1093/cercor/bhk028 (literal)
Alternative label
  • Landmann Claire; Dehaene Stanislas; Pappata Sabina; Jobert Antoinette; Bottlaender Michel; Roumenov Dimitri; Le Bihan Denis (2007)
    Dynamics of prefrontal and cingulate activity during a reward-based logical deduction task.
    in Cerebral cortex (N. Y. N. Y., 1991); Oxford University Press Inc., Cary (Stati Uniti d'America)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Landmann Claire; Dehaene Stanislas; Pappata Sabina; Jobert Antoinette; Bottlaender Michel; Roumenov Dimitri; Le Bihan Denis (literal)
Pagina inizio
  • 749 (literal)
Pagina fine
  • 759 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 17 (literal)
Rivista
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • INSERM, Serv Hosp Frederic Joliot, Commiss Energy Atom, Dept Rech Med,Direct Sci Vivant, F-91401 Orsay, France Coll France, F-75231 Paris 05, France CNR, Ist Biostrutture & Bioimmagini, I-80131 Naples, Italy CEA, Serv Hosp Frederic Joliot, Dept Rech Med, Direct Sci Vivant, F-91406 Orsay, France CEA, Serv Hosp Frederic Joliot, Direct Sci Vivant, Unite Neuroimagerie Anatomofonct, F-91401 Orsay, France (literal)
Titolo
  • Dynamics of prefrontal and cingulate activity during a reward-based logical deduction task. (literal)
Abstract
  • We used behavioral and functional magnetic resonance imaging (fMRI) methods to probe the cerebral organization of a simple logical deduction process. Subjects were engaged in a motor trial-and-error learning task, in which they had to infer the identity of an unknown 4-key code. The design of the task allowed subjects to base their inferences not only on the feedback they received but also on the internal deductions that it afforded (autoevaluation). fMRI analysis revealed a large bilateral parietal, prefrontal, cingulate, and striatal network that activated suddenly during search periods and collapsed during ensuing periods of sequence repetition. Fine-grained analyses of the temporal dynamics of this search network indicated that it operates according to near-optimal rules that include 1) computation of the difference between expected and obtained rewards and 2) anticipatory deductions that predate the actual reception of positive reward. In summary, the dynamics of effortful mental deduction can be tracked with fMRI and relate to a distributed network engaging prefrontal cortex and its interconnected cortical and subcortical regions. (literal)
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