http://www.cnr.it/ontology/cnr/individuo/prodotto/ID13566
Prognostic value of myocardial ischemia in patients with uncomplicated acute myocardial infarction: Direct comparison of stress echocardiography and myocardial perfusion imaging (Articolo in rivista)
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- Label
- Prognostic value of myocardial ischemia in patients with uncomplicated acute myocardial infarction: Direct comparison of stress echocardiography and myocardial perfusion imaging (Articolo in rivista) (literal)
- Anno
- 2005-01-01T00:00:00+01:00 (literal)
- Alternative label
Acampa, W; Spinelli, L; Petretta, M; De Lauro, F; Ibello, F; Cuocolo, A (2005)
Prognostic value of myocardial ischemia in patients with uncomplicated acute myocardial infarction: Direct comparison of stress echocardiography and myocardial perfusion imaging
in The Journal of nuclear medicine (1978)
(literal)
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- Acampa, W; Spinelli, L; Petretta, M; De Lauro, F; Ibello, F; Cuocolo, A (literal)
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- University of Naples Federico II; Consiglio Nazionale delle Ricerche (CNR); Neuromed; University of Naples Federico II (literal)
- Titolo
- Prognostic value of myocardial ischemia in patients with uncomplicated acute myocardial infarction: Direct comparison of stress echocardiography and myocardial perfusion imaging (literal)
- Abstract
- This study directly compared the prognostic value of predischarge dobutamine stress echocardiography (DSE) and dobutamine myocardial SPECT perfusion imaging in patients with prior myocardial infarction. Methods: The study population consisted of 146 consecutive patients who underwent predischarge DSE and SPECT with Tc-99m-sestamibi after a first acute uncomplicated myocardial infarction treated with thrombolysis. Fifty patients who underwent revascularization within 90 d from the imaging studies were excluded. Cardiac death and nonfatal myocardial infarction were considered events. Follow-up was 98% complete in a mean period of 44 +/- 19 mo. Results: Myocardial ischemia was detectable in 55 (58%) patients at SPECT and in 63 (67%) patients at DSE. Concordance between SPECT and DSE in detecting ischemia was observed in 68 (72%) of the 94 patients (K value, 0.41). During the follow-up, there were 20 cardiac events (9 deaths and 11 nonfatal myocardial infarctions). Ischemia at SPECT was a significant predictor of events (hazards ratio = 4.8; 95% confidence interval, 1.4-16.3; P < 0.01). However, ischemia at DSE (biphasic or worsening patterns) was not associated with events, whereas biphasic pattern alone was associated with a poor outcome compared with direct worsening (P < 0.05). Finally, at Cox multivariate analysis, ischemia at SPECT but not biphasic pattern at DSE was a significant independent predictor of events (P < 0.01). Conclusion: These results indicate that, after uncomplicated myocardial infarction, ischemia at SPECT is associated with an increased risk of cardiac events at long-term follow-up. However, ischemia at DSE was unable to stratify patients after myocardial infarction. (literal)
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