http://www.cnr.it/ontology/cnr/individuo/prodotto/ID135259
The role of oxidative damage to nucleic acids in the pathogenesis of cardiovascular disease (Contributo in volume (capitolo o saggio))
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- Label
- The role of oxidative damage to nucleic acids in the pathogenesis of cardiovascular disease (Contributo in volume (capitolo o saggio)) (literal)
- Anno
- 2007-01-01T00:00:00+01:00 (literal)
- Alternative label
Andreassi M. G. (2007)
The role of oxidative damage to nucleic acids in the pathogenesis of cardiovascular disease
Landes Bioscience, Georgetown, TX, USA, 2007
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- Andreassi M. G. (literal)
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- Georgetown, TX, USA (literal)
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- In: Oxidative Damage to Nucleic Acids. pp. 0 - 0. Evans, MD & Cooke, MS (eds.). Landes Bioscience, 2007. (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#descrizioneSinteticaDelProdotto
- Cardiovascular disease is the dominant health problem in the western world. The most frequent underlying cause of cardiovascular disease is atherosclerosis. The cellular and molecular mechanisms involved in atherosclerosis and its acute complications are being defined, but much is still unknown. Growing evidence indicates that oxidative damage to nuclear and mitochondrial DNA may represent an important link between the inflammatory nature and the oxidative theory of atherosclerosis. Various animal models of atherosclerosis support the evidence that oxidatively damaged DNA plays a key role in both the formation and the complications of atherosclerosis. Human investigations also support a mutational hypothesis of atherosclerosis. Future research on the mechanism by which oxidatively damaged DNA participates in the atherogenic process may provide new insights for early diagnosis and treatment of atherosclerosis. (literal)
- Titolo
- The role of oxidative damage to nucleic acids in the pathogenesis of cardiovascular disease (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#inCollana
- Oxidative Damage to Nucleic Acids (literal)
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