Molecular mechanisms and side-effects of viral RNA silencing suppressors (Comunicazione a convegno)

Type
Label
  • Molecular mechanisms and side-effects of viral RNA silencing suppressors (Comunicazione a convegno) (literal)
Anno
  • 2008-01-01T00:00:00+01:00 (literal)
Alternative label
  • Corba Tibor, Lozsa Rita, Lakatos Lóránt and József Burgyán (2008)
    Molecular mechanisms and side-effects of viral RNA silencing suppressors
    in XIV International Congress of Virology, Istambul, Turkey
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Corba Tibor, Lozsa Rita, Lakatos Lóránt and József Burgyán (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#descrizioneSinteticaDelProdotto
  • Viruses are inducers, as well as targets, of RNA silencing-based antiviral defence. Replication intermediates or folded viral RNAs activate RNA silencing, generating small interfering RNAs (siRNAs), which are the key players in the antiviral response. Viruses are able to counteract RNA silencing by expressing silencing-suppressor proteins. It has been shown that many of the identified silencing-suppressor proteins bind long double-stranded RNA or siRNAs and thereby prevent assembly of the RNA-induced silencing complex (RISC), which targets the corresponding viral RNA for degradation. However, recently identified suppressor proteins have been shown to interact with the protein components of silencing machinery preventing the target viral RNA degradation. The molecular bases of the silencing suppressor strategies and their effects on endogenous silencing pathways will be also discussed (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Agricultural Biotechnology Center, Godollo (Hungary) (literal)
Titolo
  • Molecular mechanisms and side-effects of viral RNA silencing suppressors (literal)
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