http://www.cnr.it/ontology/cnr/individuo/prodotto/ID13075
Distribution of artemisinin and bioactive flavonoids from Artemisia annua L. during plant growth (Articolo in rivista)
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- Label
- Distribution of artemisinin and bioactive flavonoids from Artemisia annua L. during plant growth (Articolo in rivista) (literal)
- Anno
- 2008-01-01T00:00:00+01:00 (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
- 10.1016/j.bse.2007.11.002 (literal)
- Alternative label
Baraldi, R (Baraldi, Rita)1; Isacchi, B (Isacchi, Benedetta)2; Predieri, S (Predieri, Stefano)1; Marconi, G (Marconi, Giancarlo)3; Vincieri, FF (Vincieri, Franco Francesco)2; Bilia, AR (Bilia, Anna Rita)2 (2008)
Distribution of artemisinin and bioactive flavonoids from Artemisia annua L. during plant growth
in Biochemical systematics and ecology
(literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Baraldi, R (Baraldi, Rita)1; Isacchi, B (Isacchi, Benedetta)2; Predieri, S (Predieri, Stefano)1; Marconi, G (Marconi, Giancarlo)3; Vincieri, FF (Vincieri, Franco Francesco)2; Bilia, AR (Bilia, Anna Rita)2 (literal)
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- ISI Web of Science (WOS) (literal)
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- 1. CNR, Natl Res Council, Ist Biometeorol, I-40129 Bologna, Italy
2. Univ Florence, Dipartimento Sci Farmaceut, I-50019 Florence, Italy
3. CNR, Ist Sintesi Organ & Fotoreattivita, I-40129 Bologna, Italy (literal)
- Titolo
- Distribution of artemisinin and bioactive flavonoids from Artemisia annua L. during plant growth (literal)
- Abstract
- Artemisia annua L. (Qinghao, Asteraceae) is a promising and potent antimalarial herbal drug. Its activity has been ascribed to the content of artemisinin, a sesquiterpene lactone that is very effective against drug-resistant Plasmodium. Many studies have pointed out that the presence of polymethoxyflavonoids in the phytocomplex can enhance the bioavailability or the activity of artemisinin. In this study the production of both artemisinin and flavonoids by plants of an aromatic ecotype of Artemisia annua L. was characterized in different aerial parts of the plants at different developmental stages. The qualitative profile of the investigated plant parts was similar; in addition to artemisinin, four flavonoids were identified: chrysoplenetin, casticin, eupatin and artemetin. The highest contents of both flavonoids and artemisinin were found at the full blooming stage. At this developmental stage, artemisinin was higher in leaves than in inflorescences, while the total flavonoid levels were similar in both plant organs. (literal)
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