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Proteasome function is required for activation of programmed cell death in heat shocked tobacco Bright-Yellow 2 cells (Articolo in rivista)
- Type
- Label
- Proteasome function is required for activation of programmed cell death in heat shocked tobacco Bright-Yellow 2 cells (Articolo in rivista) (literal)
- Anno
- 2007-01-01T00:00:00+01:00 (literal)
- Alternative label
Vacca RA, Valenti D, Bobba A, de Pinto MC, Merafina RS, De Gara L, Passarella S, Marra E. (2007)
Proteasome function is required for activation of programmed cell death in heat shocked tobacco Bright-Yellow 2 cells
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- Vacca RA, Valenti D, Bobba A, de Pinto MC, Merafina RS, De Gara L, Passarella S, Marra E. (literal)
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- ISI Web of Science (WOS) (literal)
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- Istituto di Biomembrane e Bioenergetica, Consiglio Nazionale delle Ricerche Bari.
Dipartimento di Biologia e Patologia Vegetale, Universita degli Studi di Bari.
Dipartimento di Scienze della Salute, Università del Molise,Campobasso. (literal)
- Titolo
- Proteasome function is required for activation of programmed cell death in heat shocked tobacco Bright-Yellow 2 cells (literal)
- Abstract
- To find out whether and how proteasome is involved in plant programmed cell death (PCD) we measured proteasome function in tobacco cells undergoing PCD as a result of heat shock (HS-PCD). Reactive oxygen species (ROS) production, cytochrome c levels and caspase-3-like protease activation were also measured in the absence or presence of MG132, a proteasome inhibitor. We show that proteasome activation occurs in early phase of HS-PCD upstream of the caspase-like proteases activation; moreover inhibition of proteasome function by MG132 results in prevention of PCD perhaps due to the prevention of ROS production, cytochrome c release and caspase-3-like protease activation. (literal)
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