A 50 Hz sinusoidal magnetic field does not damage MG-63 three-dimensional tumor spheroids but induces changes in their invasive properties (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• A 50 Hz sinusoidal magnetic field does not damage MG-63 three-dimensional tumor spheroids but induces changes in their invasive properties (Articolo in rivista) (literal)

Anno

• 2006-01-01T00:00:00+01:00 (literal)

Alternative label

• Santini, MT; Rainaldi, G; Ferrante, A; Indovina, P; Donelli, G; Indovina, PL (2006)
  A 50 Hz sinusoidal magnetic field does not damage MG-63 three-dimensional tumor spheroids but induces changes in their invasive properties
  in Bioelectromagnetics
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Santini, MT; Rainaldi, G; Ferrante, A; Indovina, P; Donelli, G; Indovina, PL (literal)

Pagina inizio

• 132 (literal)

Pagina fine

• 141 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 27 (literal)

Rivista

• Bioelectromagnetics (Rivista)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Ist Super Sanita, Dipartimento Ematol Oncol & Med Mol, I-00161 Rome, Italy; CNR, INFM, Unita Napoli, I-80125 Naples, Italy; Ist Super Sanita, Dipartimento Tecnol & Salute, I-00161 Rome, Italy; Univ Naples Federico II, Dipartimento Sci Fisiche, Naples, Italy (literal)

Titolo

• A 50 Hz sinusoidal magnetic field does not damage MG-63 three-dimensional tumor spheroids but induces changes in their invasive properties (literal)

Abstract

• The possibility that a sinusoidal 50 Hz magnetic field with a magnetic flux density of 1 mT can damage MG-63 osteosarcoma spheroids and induce variations in the invasive properties of these three-dimensional model systems after 2 days of exposure was investigated. Specifically, possible damage induced by these fields was examined by determining chances in spheroid surface morphology (light microscopy), growth (spheroid diameter and protein content determination), lactate dehydrogenase release, and reduced glutathione amount. Possible changes in the invasive properties were studied by invasion chambers. The results show no induction of cell damage by ELF fields while invasion chamber assays demonstrate a significant increase in the invasive potential of exposed spheroids. In order to determine if the fibronectin or hyaluronan receptors are involved, Western blot analysis was conducted on these two proteins. No significant variations were observed in either receptor in MG-63 multicellular tumor spheroids. (literal)

Prodotto di

• Aspetti fondamentali della fisica delle perovskiti (MD.P04.018.001) (Modulo)

Autore CNR

• PIETRO LUIGI INDOVINA (Unità di personale esterno)

Insieme di parole chiave

• Parole chiave di "A 50 Hz sinusoidal magnetic field does not damage MG-63 three-dimensional tumor spheroids but induces changes in their invasive properties" (Insieme di parole chiave)

Incoming links:

Prodotto

• Aspetti fondamentali della fisica delle perovskiti (MD.P04.018.001) (Modulo)

Autore CNR di

• PIETRO LUIGI INDOVINA (Unità di personale esterno)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Bioelectromagnetics (Rivista)

Insieme di parole chiave di

• Parole chiave di "A 50 Hz sinusoidal magnetic field does not damage MG-63 three-dimensional tumor spheroids but induces changes in their invasive properties" (Insieme di parole chiave)