HELICOBACTER PYLORI IS ASSOCIATED WITH MODIFIED LIPID PROFILE: IMPACT ON LIPOPROTEIN(A). (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• HELICOBACTER PYLORI IS ASSOCIATED WITH MODIFIED LIPID PROFILE: IMPACT ON LIPOPROTEIN(A). (Articolo in rivista) (literal)

Anno

• 2003-01-01T00:00:00+01:00 (literal)

Alternative label

• Chimienti G, Russo F, Lamanuzzi BL, Nardulli M, Messa C, Di Leo A, Correale M, Giannuzzi V, Pepe G. (2003)
  HELICOBACTER PYLORI IS ASSOCIATED WITH MODIFIED LIPID PROFILE: IMPACT ON LIPOPROTEIN(A).
  in Clinical biochemistry
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Chimienti G, Russo F, Lamanuzzi BL, Nardulli M, Messa C, Di Leo A, Correale M, Giannuzzi V, Pepe G. (literal)

Pagina inizio

• 359 (literal)

Pagina fine

• 365 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 36 (literal)

Rivista

• Clinical biochemistry (Rivista)

Note

• ISI Web of Science (WOS) (literal)

Titolo

• HELICOBACTER PYLORI IS ASSOCIATED WITH MODIFIED LIPID PROFILE: IMPACT ON LIPOPROTEIN(A). (literal)

Abstract

• OBJECTIVES: Helicobacter pylori is a controversial risk factor for atherosclerosis. We investigated whether the bacterium persistent inflammation or the expression of the cytotoxin-associated gene A (CagA) may affect serum lipids as well as Lipoprotein(a). DESIGN AND METHODS: Two hundred-eleven healthy volunteers were evaluated for lipids and Lipoprotein(a). Helicobacter pylori was characterized by Urea Breath Test and IgG-anti-CagA. apo(a) Kringle-IV polymorphism was genotyped. RESULTS: Prevalence of the infection was 72%; 43% of subjects expressed CagA reactivity. Infected subjects showed increased levels of cholesterol, LDL-cholesterol, and cholesterol/HDL-cholesterol atherogenic index. Association with the Helicobacter pylori CagA(-) strains persisted after the adjustment for covariates. Significant difference between infected and uninfected subjects was found in Lipoprotein(a) levels. This difference did not arise from the Kringle-IV genotype. CONCLUSIONS: The infection per se significantly modified serum lipid and Lipoprotein(a) concentrations. CagA does not seem to be a reliable marker of pathogenicity for the atherogenic complications of H. pylori infection. (literal)

Prodotto di

• Institute of biomembrane and bioenergetics (IBBE) (Istituto)

Incoming links:

Prodotto

• Institute of biomembrane and bioenergetics (IBBE) (Istituto)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Clinical biochemistry (Rivista)