Airway inflammation in nonasthmatic amateur runners. (Articolo in rivista)

Type
Label
  • Airway inflammation in nonasthmatic amateur runners. (Articolo in rivista) (literal)
Anno
  • 2001-01-01T00:00:00+01:00 (literal)
Alternative label
  • MARIA R. BONSIGNORE,1 GIUSEPPE MORICI,2 LOREDANA RICCOBONO,1 GIUSEPPE INSALACO,1 ANNA BONANNO,1 MIRELLA PROFITA,1 ALESSANDRA PATERNO` ,1 CRISTINA VASSALLE,3 ANGELA MIRABELLA,4 AND A. MAURIZIO VIGNOLA4 (2001)
    Airway inflammation in nonasthmatic amateur runners.
    in American journal of physiology. Lung cellular and molecular physiology
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • MARIA R. BONSIGNORE,1 GIUSEPPE MORICI,2 LOREDANA RICCOBONO,1 GIUSEPPE INSALACO,1 ANNA BONANNO,1 MIRELLA PROFITA,1 ALESSANDRA PATERNO` ,1 CRISTINA VASSALLE,3 ANGELA MIRABELLA,4 AND A. MAURIZIO VIGNOLA4 (literal)
Pagina inizio
  • L668 (literal)
Pagina fine
  • L676 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 281 (literal)
Rivista
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • 1Institute of Respiratory Pathophysiology, Italian National Research Council, 2Institute of Human Physiology, and 4Institute of Pneumology, University of Palermo, 90146 Palermo; and 3Instituteof Clinical Physiology, Italian National Research Council, 56126 Pisa, Italy (literal)
Titolo
  • Airway inflammation in nonasthmatic amateur runners. (literal)
Abstract
  • Elite athletes show a high prevalence of symptoms and signs of asthma, but no study has assessed the acute effects of endurance exercise on airway cells in nonasthmatic athletes. We measured exhaled nitric oxide (NO) and collected samples of induced sputum after 3% NaCl aerosol administration for 20 min in nonasthmatic middle-aged amateur runners after the Fourth Palermo International Marathon and 6-9 wk later (habitual training period) at baseline. After the marathon, exhaled NO (n 5 9 subjects) was higher [27 6 9 parts/billion (ppb)] than at baseline (12 6 4 ppb; P , 0.0005). Polymorphonuclear neutrophil (PMN) counts in induced sputum were much higher in runners (91.2 6 3.6% of total cells postmarathon and 78.7 6 9.1% at baseline) than in sedentary control subjects (9.9 6 5.9%; P , 0.001). Expression of L-selectin and CD11b/CD18 in sputum PMNs was lower after the race than at baseline and inversely related to the amount of exhaled NO (r 5 20.66 and 20.69, respectively; P , 0.05). Our data indicate that sputum PMNs are increased in nonasthmatic runners both after a marathon and at baseline and suggest that NO may modulate exercise-associated inflammatory airway changes. (literal)
Prodotto di
Autore CNR
Insieme di parole chiave

Incoming links:


Autore CNR di
Prodotto
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi
Insieme di parole chiave di
data.CNR.it